RNF31 and ATG13

Number of citations of the paper that reports this interaction (PubMedID 32543267)
7

Data Source:
BioGRID (enzymatic study)

		RNF31	ATG13
Description		ring finger protein 31	autophagy related 13
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GO Annotations	Cellular Component	Cytosol Cytoplasmic Side Of Plasma Membrane CD40 Receptor Complex LUBAC Complex	Phagophore Assembly Site Mitochondrion Endoplasmic Reticulum Membrane Cytosol Extrinsic Component Of Membrane Atg1/ULK1 Kinase Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin Protein Ligase Binding K48-linked Polyubiquitin Modification-dependent Protein Binding Identical Protein Binding Ubiquitin Binding Metal Ion Binding Ubiquitin Protein Ligase Activity K63-linked Polyubiquitin Modification-dependent Protein Binding Linear Polyubiquitin Binding	Protein Binding Protein Kinase Binding
	Biological Process	Protein Polyubiquitination CD40 Signaling Pathway Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling T Cell Receptor Signaling Pathway Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Linear Polyubiquitination Positive Regulation Of Protein Targeting To Mitochondrion	Autophagosome Assembly Mitophagy Protein Localization To Phagophore Assembly Site Piecemeal Microautophagy Of The Nucleus Positive Regulation Of Protein Targeting To Mitochondrion
Pathways		Regulation of TNFR1 signaling TNFR1-induced NFkappaB signaling pathway	Macroautophagy
Drugs
Diseases
GWAS		Suicide behavior ( 26079190)	Age at first sexual intercourse ( 27089180) Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Autism spectrum disorder or schizophrenia ( 28540026) Headache ( 29397368) Immunoglobulin A ( 20694011) Reaction time ( 29844566) Schizophrenia ( 29483656) Selective IgA deficiency ( 27723758)
Interacting Genes		51 interacting genes: ATG13 ATN1 ATXN1 ATXN7 AZI2 CASP1 CASP6 CASP8 CCDC24 CDC34 GFI1B HDAC6 IKBKG KIF1A KRTAP9-2 NOS3 NR0B1 NR0B2 PITX1 PRKCA RBCK1 SEPTIN2 SMAD3 SNRPC SOCS3 SPATA2 STK4 TLE5 TRAF1 TRAF6 TRIM25 TSSC4 UBC UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2K UBE2L3 UBE2O UBE2Q1 UBE2Q2 UBE2R2 UBE2T UBE2W VASN VDAC1	11 interacting genes: APP ATG101 ATG14 GABARAP GABARAPL1 GABARAPL2 MAP1LC3A MAP1LC3B MAP1LC3C RNF31 SMCR8
Entrez ID		55072	9776
HPRD ID		11516	13809
Ensembl ID		ENSG00000092098	ENSG00000175224
Uniprot IDs		Q96EP0	A8K0S6 O75143
PDB IDs		2CT7 4DBG 4JUY 4LJO 4LJP 4LJQ 4OWF 4OYJ 4OYK 4P09 4P0A 4P0B 5EDV 5LJN 5X0W 6GZY 6KC5 6KC6 6SC5 6SC6 6SC7 6SC8 6SC9	3WAN 3WAO 3WAP 5C50 5XUY 5XV1 5XV3 5XV4 5XV6 6HYN
Enriched GO Terms of Interacting Partners?
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