CCL22 and VCAM1

Number of citations of the paper that reports this interaction (PubMedID 12193695)
17

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		CCL22	VCAM1
Description		C-C motif chemokine ligand 22	vascular cell adhesion molecule 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Podosome Extracellular Space Early Endosome Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Microvillus External Side Of Plasma Membrane Cell Surface Filopodium Sarcolemma Apical Part Of Cell Extracellular Exosome Alpha9-beta1 Integrin-vascular Cell Adhesion Molecule-1 Complex
	Molecular Function	Protein Binding Chemokine Activity CCR Chemokine Receptor Binding	Integrin Binding Primary Amine Oxidase Activity Cell Adhesion Molecule Binding
	Biological Process	Monocyte Chemotaxis Chemotaxis Inflammatory Response Immune Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Response To Virus Neutrophil Chemotaxis Positive Regulation Of GTPase Activity Lymphocyte Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor	Response To Hypoxia Acute Inflammatory Response Chronic Inflammatory Response Cell Adhesion Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Leukocyte Cell-cell Adhesion Cell-matrix Adhesion Aging Response To Nutrient Amine Metabolic Process Response To Zinc Ion Response To Ionizing Radiation Membrane To Membrane Docking B Cell Differentiation Response To Lipopolysaccharide Heterotypic Cell-cell Adhesion Response To Nicotine Calcium-mediated Signaling Using Intracellular Calcium Source Cellular Response To Vascular Endothelial Growth Factor Stimulus Positive Regulation Of T Cell Proliferation Response To Ethanol Leukocyte Tethering Or Rolling Cell Chemotaxis Innervation Cardiac Neuron Differentiation Cellular Response To Tumor Necrosis Factor Cell-cell Adhesion In Response To Extracellular Stimulus Cellular Response To Amyloid-beta
Pathways		Chemokine receptors bind chemokines Interleukin-10 signaling Interleukin-4 and Interleukin-13 signaling	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Integrin cell surface interactions Interleukin-4 and Interleukin-13 signaling Interferon gamma signaling
Drugs			Ethanol Carvedilol Succinobucol Clove oil
Diseases
GWAS		Asthma ( 32296059) Blood protein levels ( 30072576 29875488) Multiple sclerosis ( 24076602) Systemic lupus erythematosus ( 33272962 28714469)	Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Multiple sclerosis ( 31604244 24076602 21833088) Neutrophil percentage of white cells ( 32888494) SjÃ¶gren's syndrome ( 24097067)
Interacting Genes		11 interacting genes: AQP6 CCL14 CCL19 CCR4 CRYAB DPP4 GCLC HERC3 NLGN4X PF4V1 VCAM1	15 interacting genes: CCL17 CCL22 CTSG ELANE ETFA EXOSC2 EZR IL13 ITGAD ITGB1 ITGB7 MSN TRIM54 TRIM65 USP2
Entrez ID		6367	7412
HPRD ID		04263	01888
Ensembl ID		ENSG00000102962	ENSG00000162692
Uniprot IDs		O00626	P19320
PDB IDs			1IJ9 1VCA 1VSC
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?