VCAM1 and CCL17

Number of citations of the paper that reports this interaction (PubMedID 12193695)
17

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		VCAM1	CCL17
Description		vascular cell adhesion molecule 1	C-C motif chemokine ligand 17
Image
GO Annotations	Cellular Component	Podosome Extracellular Space Early Endosome Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Microvillus External Side Of Plasma Membrane Cell Surface Filopodium Sarcolemma Apical Part Of Cell Extracellular Exosome Alpha9-beta1 Integrin-vascular Cell Adhesion Molecule-1 Complex	Extracellular Region Extracellular Space
	Molecular Function	Integrin Binding Primary Amine Oxidase Activity Cell Adhesion Molecule Binding	Signaling Receptor Binding Protein Binding Chemokine Activity CCR4 Chemokine Receptor Binding CCR Chemokine Receptor Binding
	Biological Process	Response To Hypoxia Acute Inflammatory Response Chronic Inflammatory Response Cell Adhesion Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Leukocyte Cell-cell Adhesion Cell-matrix Adhesion Aging Response To Nutrient Amine Metabolic Process Response To Zinc Ion Response To Ionizing Radiation Membrane To Membrane Docking B Cell Differentiation Response To Lipopolysaccharide Heterotypic Cell-cell Adhesion Response To Nicotine Calcium-mediated Signaling Using Intracellular Calcium Source Cellular Response To Vascular Endothelial Growth Factor Stimulus Positive Regulation Of T Cell Proliferation Response To Ethanol Leukocyte Tethering Or Rolling Cell Chemotaxis Innervation Cardiac Neuron Differentiation Cellular Response To Tumor Necrosis Factor Cell-cell Adhesion In Response To Extracellular Stimulus Cellular Response To Amyloid-beta	Monocyte Chemotaxis Chemotaxis Inflammatory Response G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Multicellular Organism Development Neutrophil Chemotaxis Positive Regulation Of GTPase Activity Negative Regulation Of Myoblast Differentiation Lymphocyte Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Integrin cell surface interactions Interleukin-4 and Interleukin-13 signaling Interferon gamma signaling	Chemokine receptors bind chemokines
Drugs		Ethanol Carvedilol Succinobucol Clove oil
Diseases
GWAS		Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Multiple sclerosis ( 31604244 24076602 21833088) Neutrophil percentage of white cells ( 32888494) SjÃ¶gren's syndrome ( 24097067)	Blood protein levels ( 30072576 29875488 28240269) Thymus and reactivation regulated chemokine levels ( 33227023)
Interacting Genes		15 interacting genes: CCL17 CCL22 CTSG ELANE ETFA EXOSC2 EZR IL13 ITGAD ITGB1 ITGB7 MSN TRIM54 TRIM65 USP2	9 interacting genes: ACKR1 CCL21 CCL25 CCL26 CCL28 CCL5 CCR4 CCR8 VCAM1
Entrez ID		7412	6361
HPRD ID		01888	03309
Ensembl ID		ENSG00000162692	ENSG00000102970
Uniprot IDs		P19320	Q92583
PDB IDs		1IJ9 1VCA 1VSC	1NR2 1NR4 5WK3
Enriched GO Terms of Interacting Partners?
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