SCN4A and PATJ

Number of citations of the paper that reports this interaction (PubMedID 16637659)
29

Data Source:
HPRD (in vitro)

		SCN4A	PATJ
Description		sodium voltage-gated channel alpha subunit 4	PATJ crumbs cell polarity complex component
Image			No pdb structure
GO Annotations	Cellular Component	Voltage-gated Sodium Channel Complex Integral Component Of Plasma Membrane Axon	Cytoplasm Cytosol Plasma Membrane Bicellular Tight Junction Apical Plasma Membrane Cell Junction Centriolar Satellite Apical Part Of Cell Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Voltage-gated Ion Channel Activity Voltage-gated Sodium Channel Activity Protein Binding	Protein Binding
	Biological Process	Sodium Ion Transport Muscle Contraction Neuronal Action Potential Regulation Of Ion Transmembrane Transport Sodium Ion Transmembrane Transport Membrane Depolarization During Action Potential Regulation Of Skeletal Muscle Contraction By Action Potential	Microtubule Organizing Center Organization Establishment Of Apical/basal Cell Polarity Intracellular Signal Transduction Regulation Of Microtubule Cytoskeleton Organization Tight Junction Assembly
Pathways		Interaction between L1 and Ankyrins Phase 0 - rapid depolarisation
Drugs		Ranolazine Topiramate Lidocaine Valproic acid Lamotrigine Carbamazepine Oxcarbazepine Propofol Cocaine Zonisamide Promethazine Flecainide Brivaracetam Tetracaine Amylocaine Propoxycaine Pramocaine Pentoxyverine Parachlorophenol Dichlorobenzyl alcohol Bioallethrin Fish oil
Diseases
GWAS		Height ( 28552196 31562340) Hip circumference adjusted for BMI ( 34021172)	3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30582445) Autism spectrum disorders (social interaction) ( 32624584) Daytime nap ( 33568662) Excessive daytime sleepiness ( 27992416) Sleep traits (multi-trait analysis) ( 27992416) Type 2 diabetes ( 30297969)
Interacting Genes		10 interacting genes: CALM1 DLG1 DLG2 DLG3 ERBIN PATJ SLC9A3R1 SNTA1 SNTB1 SNTB2	35 interacting genes: ADGRB1 ASIC3 CACNG2 CEP57L1 CINP CLDN1 CNKSR2 CRB3 CRIPT DDX18 GIPC2 GLS2 GRIN2A GRIN2B GRIN2C GRIN2D HDAC7 HOMER1 KCNA4 KCNJ10 KCNJ15 KCNJ2 KIF1B MAPK12 NECAB2 NLGN2 NRXN2 PALS1 PARD3 PAX6 PHYH PRDM16 SCN4A SCN5A TJP3
Entrez ID		6329	10207
HPRD ID		04912	04434
Ensembl ID		ENSG00000007314	ENSG00000132849
Uniprot IDs		P35499
PDB IDs		6AGF 6MBA 6MC9
Enriched GO Terms of Interacting Partners?
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