PATJ and KCNJ10

Number of citations of the paper that reports this interaction (PubMedID 9647694)
29

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		PATJ	KCNJ10
Description		PATJ crumbs cell polarity complex component	potassium inwardly rectifying channel subfamily J member 10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Bicellular Tight Junction Apical Plasma Membrane Cell Junction Centriolar Satellite Apical Part Of Cell Perinuclear Region Of Cytoplasm Extracellular Exosome	Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane Cell Body Astrocyte Projection Ciliary Base Presynapse
	Molecular Function	Protein Binding	Inward Rectifier Potassium Channel Activity Protein Binding ATP Binding ATP-activated Inward Rectifier Potassium Channel Activity
	Biological Process	Microtubule Organizing Center Organization Establishment Of Apical/basal Cell Polarity Intracellular Signal Transduction Regulation Of Microtubule Cytoskeleton Organization Tight Junction Assembly	Potassium Ion Transport Visual Perception Adult Walking Behavior Central Nervous System Myelination Regulation Of Ion Transmembrane Transport Regulation Of Long-term Neuronal Synaptic Plasticity Glutamate Reuptake Potassium Ion Homeostasis Regulation Of Resting Membrane Potential Non-motile Cilium Assembly Potassium Ion Import Across Plasma Membrane
Pathways			Activation of G protein gated Potassium channels Potassium transport channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs			Yohimbine Butamben
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30582445) Autism spectrum disorders (social interaction) ( 32624584) Daytime nap ( 33568662) Excessive daytime sleepiness ( 27992416) Sleep traits (multi-trait analysis) ( 27992416) Type 2 diabetes ( 30297969)
Interacting Genes		35 interacting genes: ADGRB1 ASIC3 CACNG2 CEP57L1 CINP CLDN1 CNKSR2 CRB3 CRIPT DDX18 GIPC2 GLS2 GRIN2A GRIN2B GRIN2C GRIN2D HDAC7 HOMER1 KCNA4 KCNJ10 KCNJ15 KCNJ2 KIF1B MAPK12 NECAB2 NLGN2 NRXN2 PALS1 PARD3 PAX6 PHYH PRDM16 SCN4A SCN5A TJP3	8 interacting genes: APP DLG1 DLG4 IL16 KCNJ16 PATJ SIAH1 SNTA1
Entrez ID		10207	3766
HPRD ID		04434	03732
Ensembl ID		ENSG00000132849	ENSG00000177807
Uniprot IDs			P78508
PDB IDs
Enriched GO Terms of Interacting Partners?
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