RYR2 and FKBP1B

  • Number of citations of the paper that reports this interaction (PubMedID 10830164)
  • 611
  • Data Source:
  • BioGRID (affinity chromatography technology, fluorescent resonance energy transfer, pull down)
  • HPRD (two hybrid, in vitro, in vivo)

RYR2

FKBP1B

Description ryanodine receptor 2 FKBP prolyl isomerase 1B
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute lymphoblastic leukemia (childhood) ( 19684603)
  • Bipolar disorder and eating disorder ( 26433762)
  • Cerivastatin-induced rhabdomyolysis ( 21386754)
  • cognitive impairment (MMSE score) in Parkinson’s disease ( 33613413)
  • Exercise treadmill test traits ( 17903301)
  • General risk tolerance (MTAG) ( 30643258)
  • Hippocampal volume ( 31530798)
  • Hypertension ( 17554300)
  • Lipid traits ( 30576415 24386095)
  • Lung function (FEV1) ( 30061609)
  • Lung function (FVC) ( 30061609)
  • Metabolite levels ( 23823483)
  • Obesity-related traits ( 23251661)
  • Postoperative stroke after cardiac surgery ( 30678657)
  • PR interval ( 32439900)
  • Response to taxane treatment (docetaxel) ( 23006423)
  • Smoking initiation (ever regular vs never regular) ( 30679032)
Interacting Genes 16 interacting genes: AKAP6 ALB CACNA1C FKBP1B HOMER1 HSPB2 ITPR1 LINC00839 MDM2 PRKACA PRKAR2A PSEN1 RYR1 RYR3 SMAD5 SRI 12 interacting genes: ADAMTSL4 BMPR1A CAMK2D GMCL1 KRT31 KRT40 KRTAP1-1 REL RYR2 RYR3 TGFBR1 TRIM69
Entrez ID 6262 2281
HPRD ID 01619 02795
Ensembl ID ENSG00000198626 ENSG00000119782
Uniprot IDs Q92736 F8W6G9 P68106
PDB IDs 4JKQ 6Y4O 6Y4P 1C9H 4C02 4IQ2 4IQC 5HKG 5L1D 5T15 5T9M 5T9N 5T9R 5T9S 5T9V 5TA3 5TAL 5TAM 5TAN 5TAP 5TAQ 5TAS 5TAT 5TAU 5TAV 5TAW 5TAX 5TAY 5TAZ 5TB0 5TB1 5TB2 5TB3 5TB4 6JGZ 6JH6 6JHN 6JI0 6JI8 6JII 6JIU 6JIY 6JRR 6JRS 6M2W 6PV6 6W1N 6WOT 6WOU 6WOV 6X32 6X33 6X34 6X35 6X36 7CF9 7JMF 7JMG 7JMH 7JMI 7JMJ
Enriched GO Terms of Interacting Partners?
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