RXRG and FBXL4

		RXRG	FBXL4
Description		retinoid X receptor gamma	F-box and leucine rich repeat protein 4
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleoplasm Cytoplasm RNA Polymerase II Transcription Regulator Complex	Ubiquitin Ligase Complex Mitochondrial Intermembrane Space Cytosol Nuclear Speck SCF Ubiquitin Ligase Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Steroid Hormone Receptor Activity Nuclear Receptor Activity Protein Binding Zinc Ion Binding Retinoic Acid-responsive Element Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Cell Differentiation Response To Retinoic Acid Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Retinoic Acid Receptor Signaling Pathway Anatomical Structure Development	Ubiquitin-dependent Protein Catabolic Process SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Pathways		Nuclear Receptor transcription pathway Signaling by Retinoic Acid	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs		Adapalene Bexarotene Rosiglitazone Acitretin Alitretinoin Tretinoin Etretinate Bezafibrate Phthalic Acid Doconexent
Diseases
GWAS		AIDS ( 19754311) Bipolar disorder (age of onset <21) or attention deficit hyperactivity disorder ( 27890468) Bipolar disorder or attention deficit hyperactivity disorder ( 27890468) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Macular thickness ( 30535121) Menarche (age at onset) ( 27182965 21102462 29773799 25231870) Metabolite levels ( 23823483) Personality traits in bipolar disorder ( 21368711) Proportion of activated microglia (midfrontal cortex) ( 30679421) Waist circumference adjusted for body mass index ( 34021172)	Chronotype ( 30696823) Depression ( 29700475) Experiencing mood swings ( 29500382) Feeling nervous ( 29500382) Major depressive disorder ( 27479909) Metabolite levels ( 23823483) Neurociticism ( 29500382) Regular attendance at a religious group ( 29970889)
Interacting Genes		33 interacting genes: CAMK2B CEBPZ CHGB CKMT1A CKMT1B CREBBP DCK FBXL4 HOXD4 ITGB3BP LRSAM1 MAP4 MPPED2 NCOA6 NCOR2 NR0B2 NR1H2 NR1H3 NR1H4 NR1I2 NR4A1 PICK1 PNO1 PPARA PPARD PPARG RARA RARB RARG SRF THRA THRB VDR	4 interacting genes: GP1BA MAP3K7 RXRG SKP1
Entrez ID		6258	26235
HPRD ID		01579	05738
Ensembl ID		ENSG00000143171	ENSG00000112234
Uniprot IDs		A0A087WZ88 F1D8Q7 F1T097 P48443	Q9UKA2
PDB IDs		2GL8 7A79
Enriched GO Terms of Interacting Partners?
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