RXRG and DCK

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		RXRG	DCK
Description		retinoid X receptor gamma	deoxycytidine kinase
Image
GO Annotations	Cellular Component	Chromatin Nucleoplasm Cytoplasm RNA Polymerase II Transcription Regulator Complex	Nucleoplasm Cytoplasm Mitochondrion Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Steroid Hormone Receptor Activity Nuclear Receptor Activity Protein Binding Zinc Ion Binding Retinoic Acid-responsive Element Binding Sequence-specific Double-stranded DNA Binding	Deoxyadenosine Kinase Activity Deoxycytidine Kinase Activity Deoxyguanosine Kinase Activity ATP Binding Deoxynucleoside Kinase Activity Protein Homodimerization Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Cell Differentiation Response To Retinoic Acid Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Retinoic Acid Receptor Signaling Pathway Anatomical Structure Development	DAMP Biosynthetic Process Pyrimidine Nucleotide Metabolic Process Phosphorylation
Pathways		Nuclear Receptor transcription pathway Signaling by Retinoic Acid	Pyrimidine salvage Purine salvage
Drugs		Adapalene Bexarotene Rosiglitazone Acitretin Alitretinoin Tretinoin Etretinate Bezafibrate Phthalic Acid Doconexent	Fludarabine 2'-Deoxycytidine Elacytarabine
Diseases
GWAS		AIDS ( 19754311) Bipolar disorder (age of onset <21) or attention deficit hyperactivity disorder ( 27890468) Bipolar disorder or attention deficit hyperactivity disorder ( 27890468) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Macular thickness ( 30535121) Menarche (age at onset) ( 27182965 21102462 29773799 25231870) Metabolite levels ( 23823483) Personality traits in bipolar disorder ( 21368711) Proportion of activated microglia (midfrontal cortex) ( 30679421) Waist circumference adjusted for body mass index ( 34021172)	Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		33 interacting genes: CAMK2B CEBPZ CHGB CKMT1A CKMT1B CREBBP DCK FBXL4 HOXD4 ITGB3BP LRSAM1 MAP4 MPPED2 NCOA6 NCOR2 NR0B2 NR1H2 NR1H3 NR1H4 NR1I2 NR4A1 PICK1 PNO1 PPARA PPARD PPARG RARA RARB RARG SRF THRA THRB VDR	5 interacting genes: DDX19B GOLM1 MED19 RXRG TFEC
Entrez ID		6258	1633
HPRD ID		01579	00507
Ensembl ID		ENSG00000143171	ENSG00000156136
Uniprot IDs		A0A087WZ88 F1D8Q7 F1T097 P48443	F5CTF3 P27707
PDB IDs		2GL8 7A79	1P5Z 1P60 1P61 1P62 2A2Z 2A30 2A7Q 2NO0 2NO1 2NO6 2NO7 2NO9 2NOA 2QRN 2QRO 2ZI3 2ZI4 2ZI5 2ZI6 2ZI7 2ZI9 2ZIA 3HP1 3IPX 3IPY 3KFX 3MJR 3QEJ 3QEN 3QEO 4JLJ 4JLK 4JLM 4JLN 4KCG 4L5B 4Q18 4Q19 4Q1A 4Q1B 4Q1C 4Q1D 4Q1E 4Q1F 5MQJ 5MQL 5MQT
Enriched GO Terms of Interacting Partners?
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