MIIP and MLLT3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MIIP	MLLT3
Description		migration and invasion inhibitory protein	MLLT3 super elongation complex subunit
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Chromosome Cytosol Transcription Elongation Factor Complex Extracellular Exosome
	Molecular Function	Protein Binding	DNA Binding Chromatin Binding Protein Binding Histone Binding Lysine-acetylated Histone Binding Modification-dependent Protein Binding
	Biological Process	Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Migration	Segment Specification Anterior/posterior Pattern Specification Gene Expression Positive Regulation Of Transcription, DNA-templated Hematopoietic Stem Cell Differentiation Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Chromatin Organization Regulation Of Stem Cell Division Positive Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway
Pathways			Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Asthma ( 31959851) Serum alkaline phosphatase levels ( 33339817) Tuberculosis ( 29036319)	Atrial fibrillation ( 29892015) Dietary fat liking ( 32516399) Estimated glomerular filtration rate ( 31152163) Hematocrit ( 32888494) Hemoglobin ( 32888494) Mean reticulocyte volume ( 32888494) Platelet distribution width ( 32888494) Response to montelukast in asthma (change in FEV1) ( 26083242) Systolic blood pressure ( 30578418)
Interacting Genes		25 interacting genes: BCAS2 CCDC120 CYSRT1 EFHC1 EIF3E FRS3 KCTD9 KPRP KRT34 MED28 MLLT3 MOB2 OIP5 OTX1 PPP1CA STK16 TCHP TEKT4 TLE5 TRIM55 TRIM63 TRIP6 USHBP1 ZDHHC17 ZNF417	20 interacting genes: AFF1 ALKBH4 APP APPBP2 BCOR CBX8 CDK6 COL6A1 EEF1A1 FAM9A H3C1 LRIF1 LRRK2 MCM6 MIIP PTN RBM48 SGK1 VAX1 ZNF572
Entrez ID		60672	4300
HPRD ID		07768	01163
Ensembl ID		ENSG00000116691	ENSG00000171843
Uniprot IDs		Q5JXC2	A0A0S2Z448 P42568
PDB IDs			2LM0 2MV7 2N4Q 2NDF 2NDG 4TMP 5HJB 5HJD 5YYF 6B7G 6L5Z 6LS6 6MIL 6MIM
Enriched GO Terms of Interacting Partners?
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