MIIP and EIF3E

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MIIP	EIF3E
Description		migration and invasion inhibitory protein	eukaryotic translation initiation factor 3 subunit E
Image		No pdb structure
GO Annotations	Cellular Component		Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 3 Complex Membrane Eukaryotic 43S Preinitiation Complex PML Body Eukaryotic 48S Preinitiation Complex Extracellular Exosome Eukaryotic Translation Initiation Factor 3 Complex, EIF3e
	Molecular Function	Protein Binding	RNA Binding Translation Initiation Factor Activity Protein Binding Cadherin Binding Protein N-terminus Binding
	Biological Process	Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Migration	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation Regulation Of Translational Initiation Positive Regulation Of Translation Negative Regulation Of Translational Initiation Positive Regulation Of MRNA Binding
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS		Asthma ( 31959851) Serum alkaline phosphatase levels ( 33339817) Tuberculosis ( 29036319)	Brain morphology (MOSTest) ( 32665545) Coffee consumption ( 31046077) Dupuytren's disease ( 28886342 21732829) Heel bone mineral density ( 30598549) Macular thickness ( 30535121) Male-pattern baldness ( 28196072) Ossification of the posterior longitudinal ligament of the spine ( 25064007)
Interacting Genes		25 interacting genes: BCAS2 CCDC120 CYSRT1 EFHC1 EIF3E FRS3 KCTD9 KPRP KRT34 MED28 MLLT3 MOB2 OIP5 OTX1 PPP1CA STK16 TCHP TEKT4 TLE5 TRIM55 TRIM63 TRIP6 USHBP1 ZDHHC17 ZNF417	34 interacting genes: ATM C4orf19 COPS6 COPS7A COPS7B COPS8 DDX24 DRC3 EIF3C EIF3L EIF4ENIF1 EPAS1 EPN2 GPAA1 GPBP1L1 HAP1 IFIT1 ISCA2 KPRP LINC01554 MAPK1IP1L MIIP MRNIP NDRG1 NSF OGT PRRC2A RUNDC3A SHBG SMAD9 TRIM27 TRIM55 TRIM63 ZNF48
Entrez ID		60672	3646
HPRD ID		07768	03734
Ensembl ID		ENSG00000116691	ENSG00000104408
Uniprot IDs		Q5JXC2	P60228
PDB IDs			3J8B 3J8C 6FEC 6YBD 6ZMW 6ZON 6ZP4 6ZVJ 7A09
Enriched GO Terms of Interacting Partners?
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