RXFP1 and RLN3

Number of citations of the paper that reports this interaction (PubMedID 14522968)
59

Data Source:
HPRD (in vivo, in vitro)

		RXFP1	RLN3
Description		relaxin family peptide receptor 1	relaxin 3
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Extracellular Region
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Hormone Binding Metal Ion Binding	G Protein-coupled Receptor Binding Hormone Activity Protein Binding
	Biological Process	Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Parturition Hormone-mediated Signaling Pathway Cell Differentiation Extracellular Matrix Organization Lung Connective Tissue Development Nipple Morphogenesis	Signal Transduction
Pathways		G alpha (s) signalling events Relaxin receptors ADORA2B mediated anti-inflammatory cytokines production	G alpha (s) signalling events G alpha (i) signalling events Relaxin receptors ADORA2B mediated anti-inflammatory cytokines production
Drugs
Diseases
GWAS		Acute lymphoblastic leukemia (childhood) ( 22076464) Waist circumference adjusted for body mass index ( 28552196)	Obesity-related traits ( 23251661)
Interacting Genes		4 interacting genes: RLN1 RLN2 RLN3 SRPK2	4 interacting genes: ODAD3 RXFP1 RXFP3 RXFP4
Entrez ID		59350	117579
HPRD ID		05975	06031
Ensembl ID		ENSG00000171509	ENSG00000171136
Uniprot IDs		A0A087WWV0 A0A0A0MT52 B3KV27 B4DGP2 Q59H16 Q9HBX9	B2RU28 K7ENX1 Q8WXF3
PDB IDs		2JM4 2M7P	2FHW 2K1V
Enriched GO Terms of Interacting Partners?
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