RXFP1 and RLN2

Number of citations of the paper that reports this interaction (PubMedID 12506116)
55

		RXFP1	RLN2
Description		relaxin family peptide receptor 1	relaxin 2
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Extracellular Region
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Hormone Binding Metal Ion Binding	Hormone Activity
	Biological Process	Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Parturition Hormone-mediated Signaling Pathway Cell Differentiation Extracellular Matrix Organization Lung Connective Tissue Development Nipple Morphogenesis	Signal Transduction Female Pregnancy Positive Regulation Of Gene Expression Positive Regulation Of Angiogenesis Regulation Of Catalytic Activity
Pathways		G alpha (s) signalling events Relaxin receptors ADORA2B mediated anti-inflammatory cytokines production	G alpha (s) signalling events Relaxin receptors ADORA2B mediated anti-inflammatory cytokines production
Drugs
Diseases
GWAS		Acute lymphoblastic leukemia (childhood) ( 22076464) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		4 interacting genes: RLN1 RLN2 RLN3 SRPK2	2 interacting genes: RXFP1 RXFP2
Entrez ID		59350	6019
HPRD ID		05975	01561
Ensembl ID		ENSG00000171509	ENSG00000107014
Uniprot IDs		A0A087WWV0 A0A0A0MT52 B3KV27 B4DGP2 Q59H16 Q9HBX9	P04090
PDB IDs		2JM4 2M7P	2MV1 6RLX
Enriched GO Terms of Interacting Partners?
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