RLN3 and RXFP4

Number of citations of the paper that reports this interaction (PubMedID 14522967)
40

Data Source:
HPRD (in vivo)

		RLN3	RXFP4
Description		relaxin 3	relaxin family peptide/INSL5 receptor 4
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	G Protein-coupled Receptor Binding Hormone Activity Protein Binding	Protein Binding G Protein-coupled Peptide Receptor Activity
	Biological Process	Signal Transduction	Neuropeptide Signaling Pathway Positive Regulation Of Feeding Behavior
Pathways		G alpha (s) signalling events G alpha (i) signalling events Relaxin receptors ADORA2B mediated anti-inflammatory cytokines production	G alpha (i) signalling events Relaxin receptors
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body shape index ( 34021172) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		4 interacting genes: ODAD3 RXFP1 RXFP3 RXFP4	10 interacting genes: ACTR10 GAPDH GJA8 KNG1 MAGED1 QDPR RLN3 TSPAN3 TTC4 TTI1
Entrez ID		117579	339403
HPRD ID		06031	16421
Ensembl ID		ENSG00000171136	ENSG00000173080
Uniprot IDs		B2RU28 K7ENX1 Q8WXF3	Q8TDU9
PDB IDs		2FHW 2K1V
Enriched GO Terms of Interacting Partners?
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