ACE2 and PTPN3

ACE2

PTPN3

Description angiotensin converting enzyme 2 protein tyrosine phosphatase non-receptor type 3
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444)
  • Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Estimated glomerular filtration rate ( 31015462)
  • HIV-associated neurocognitive disorder ( 28447399)
  • HIV-associated neurocognitive disorder (asymptomatic neurocogntive impairment) ( 28447399)
  • HIV-associated neurocognitive disorder (mild neurocognitive disorder or asymptomatic neurocognitive impairment) ( 28447399)
  • Iris color (a* coordinate) ( 30895295)
  • Iris color (b* coordinate) ( 30895295)
  • Red blood cell density in sickle cell anemia ( 28552477)
  • Serum albumin level ( 29403010)
  • Staphylococcus aureus nasal carriage (persistent) ( 26569114)
  • Triglyceride levels ( 32203549)
Interacting Genes 25 interacting genes: AGT CALM1 CDSN DEFA5 DLEU2 GHRL MAST1 MAST2 NTS PARD3 PDZK1 PTPN3 SCRIB SHANK1 SHANK2 SHANK3 SHROOM2 SLC6A19 SLC9A3R1 SLC9A3R2 SNX17 SNX27 TAMALIN TMPRSS11A TMPRSS11D 27 interacting genes: ACE2 ADAM17 AKR1C1 AKT1 CD247 DIP2A GHR HSPB1 LMO1 MAPK12 MLH1 MTMR9 NXT2 PLEKHF2 RNF111 RPS6KA1 TENT5D TFAP4 TRIM41 VCP VWA2 WDR6 YWHAB YWHAG YWHAQ ZAP70 ZCCHC10
Entrez ID 59272 5774
HPRD ID 02274 06767
Ensembl ID ENSG00000130234 ENSG00000070159
Uniprot IDs Q9BYF1 B7Z3V3 B7Z9V1 B7ZA03 P26045 Q8N4S3
PDB IDs 1R42 1R4L 1XJP 2AJF 3D0G 3D0H 3D0I 3KBH 3SCI 3SCJ 3SCK 3SCL 6ACG 6ACJ 6ACK 6CS2 6LZG 6M0J 6M17 6M18 6M1D 6VW1 7A91 7A92 7A94 7A95 7A96 7A97 7A98 7BH9 7CT5 7DF4 7DMU 7JVO 7KJ2 7KJ3 7KJ4 7KMB 7KMS 7KMZ 7KNB 7KNE 7KNH 7KNI 7L0N 7L7F 2B49 4QUM 4QUN 4RH5 4RH9 4RHG 4RI4 4RI5 4S0G 6HKS 6T36
Enriched GO Terms of Interacting Partners?
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