PTPN3 and MAPK12

  • Number of citations of the paper that reports this interaction (PubMedID 20332238)
  • 29
  • Data Source:
  • BioGRID (affinity chromatography technology, enzymatic study)

PTPN3

MAPK12

Description protein tyrosine phosphatase non-receptor type 3 mitogen-activated protein kinase 12
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444)
  • Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Estimated glomerular filtration rate ( 31015462)
  • HIV-associated neurocognitive disorder ( 28447399)
  • HIV-associated neurocognitive disorder (asymptomatic neurocogntive impairment) ( 28447399)
  • HIV-associated neurocognitive disorder (mild neurocognitive disorder or asymptomatic neurocognitive impairment) ( 28447399)
  • Iris color (a* coordinate) ( 30895295)
  • Iris color (b* coordinate) ( 30895295)
  • Red blood cell density in sickle cell anemia ( 28552477)
  • Serum albumin level ( 29403010)
  • Staphylococcus aureus nasal carriage (persistent) ( 26569114)
  • Triglyceride levels ( 32203549)
Interacting Genes 27 interacting genes: ACE2 ADAM17 AKR1C1 AKT1 CD247 DIP2A GHR HSPB1 LMO1 MAPK12 MLH1 MTMR9 NXT2 PLEKHF2 RNF111 RPS6KA1 TENT5D TFAP4 TRIM41 VCP VWA2 WDR6 YWHAB YWHAG YWHAQ ZAP70 ZCCHC10 29 interacting genes: DLG1 DLG2 DLG3 DLG4 DUSP1 EEF2K ERBIN GRB2 GTF2I HTRA2 MAP2K3 MAP2K4 MAP2K6 MAPKAPK5 MAPT MBP PATJ PDGFRL PKN1 PTPN3 PTPN4 RCSD1 RGS3 SH3BP5 SIAH1 SNTA1 SNTB1 SRPK1 TERF1
Entrez ID 5774 6300
HPRD ID 06767 03868
Ensembl ID ENSG00000070159 ENSG00000188130
Uniprot IDs B7Z3V3 B7Z9V1 B7ZA03 P26045 Q8N4S3 P53778 Q6N076
PDB IDs 2B49 4QUM 4QUN 4RH5 4RH9 4RHG 4RI4 4RI5 4S0G 6HKS 6T36 1CM8 4QUM 6UNA
Enriched GO Terms of Interacting Partners?
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