PTPN3 and GHR

  • Number of citations of the paper that reports this interaction (PubMedID 12907755)
  • 20
  • Data Source:
  • BioGRID (pull down, far western blotting)

PTPN3

GHR

Description protein tyrosine phosphatase non-receptor type 3 growth hormone receptor
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444)
  • Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Estimated glomerular filtration rate ( 31015462)
  • HIV-associated neurocognitive disorder ( 28447399)
  • HIV-associated neurocognitive disorder (asymptomatic neurocogntive impairment) ( 28447399)
  • HIV-associated neurocognitive disorder (mild neurocognitive disorder or asymptomatic neurocognitive impairment) ( 28447399)
  • Iris color (a* coordinate) ( 30895295)
  • Iris color (b* coordinate) ( 30895295)
  • Red blood cell density in sickle cell anemia ( 28552477)
  • Serum albumin level ( 29403010)
  • Staphylococcus aureus nasal carriage (persistent) ( 26569114)
  • Triglyceride levels ( 32203549)
Interacting Genes 27 interacting genes: ACE2 ADAM17 AKR1C1 AKT1 CD247 DIP2A GHR HSPB1 LMO1 MAPK12 MLH1 MTMR9 NXT2 PLEKHF2 RNF111 RPS6KA1 TENT5D TFAP4 TRIM41 VCP VWA2 WDR6 YWHAB YWHAG YWHAQ ZAP70 ZCCHC10 45 interacting genes: AP2A1 BTRC CISH CLCC1 CUL1 CUL5 DUSP7 ELOB ELOC FBXO31 GH1 GH2 GRB10 GRB2 IRS1 JAK1 JAK2 NCOA6 NEDD8 PIK3R1 PIK3R2 PLCG1 PTPN1 PTPN11 PTPN13 PTPN2 PTPN3 PTPN6 PTPN9 PTPRB PTPRH RBX1 RNF7 SGTA SHC1 SKP1 SOCS1 SOCS2 SOCS3 SRPK2 STAT3 STAT5A STAT5B STUB1 TYK2
Entrez ID 5774 2690
HPRD ID 06767 02971
Ensembl ID ENSG00000070159 ENSG00000112964
Uniprot IDs B7Z3V3 B7Z9V1 B7ZA03 P26045 Q8N4S3 A0A087X0H5 A0A087X162 P10912
PDB IDs 2B49 4QUM 4QUN 4RH5 4RH9 4RHG 4RI4 4RI5 4S0G 6HKS 6T36 1A22 1AXI 1HWG 1HWH 1KF9 2AEW 3HHR 5OEK 5OHD
Enriched GO Terms of Interacting Partners?
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