CIP2A and TOPBP1

Number of citations of the paper that reports this interaction (PubMedID 34145035)
0

Data Source:
BioGRID (two hybrid)

		CIP2A	TOPBP1
Description		cellular inhibitor of PP2A	DNA topoisomerase II binding protein 1
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Integral Component Of Membrane	Condensed Nuclear Chromosome Spindle Pole Male Germ Cell Nucleus Nucleus Nucleoplasm Chromosome Cytoplasm Microtubule Organizing Center Plasma Membrane Actin Cytoskeleton Nuclear Body PML Body Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Protein Homodimerization Activity Cadherin Binding	DNA Binding Protein Binding Protein C-terminus Binding Identical Protein Binding
	Biological Process		DNA Metabolic Process DNA Replication Initiation DNA Repair Cellular Response To DNA Damage Stimulus Mitotic G2 DNA Damage Checkpoint Signaling Response To Ionizing Radiation Mitotic DNA Replication Checkpoint Signaling
Pathways			HDR through Single Strand Annealing (SSA) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Regulation of TP53 Activity through Phosphorylation G2/M DNA damage checkpoint
Drugs
Diseases
GWAS			Iron status biomarkers ( 19084217)
Interacting Genes		11 interacting genes: ATIC CSNK2B GOLGA4 LAMB2 MYC PIK3R1 STUB1 SYNCRIP TOPBP1 UBR5 WWC3	34 interacting genes: ABL1 AKT1 ATM BLM BMPR2 BRIP1 CDC45 CHEK1 CIP2A CLSTN1 E2F1 ESR1 FHL3 GINS1 HUS1 NPHP3 PML POLE PPHLN1 PPP1CC RAD1 RAD9A RAI1 RBBP8 RHNO1 SF3B2 SMARCAD1 TBC1D4 TCFL5 TEX11 TICRR TOP2B UBR5 ZBTB17
Entrez ID		57650	11073
HPRD ID		11151	09678
Ensembl ID		ENSG00000163507	ENSG00000163781
Uniprot IDs		Q8TCG1	A0AV47 A7E2X7 Q05BV8 Q92547
PDB IDs		5UFL	1WF6 2XNH 2XNK 3AL2 3AL3 3JVE 3OLC 3PD7 3UEN 3UEO 6RML 6RMM
Enriched GO Terms of Interacting Partners?
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