USP28 and TP53BP1

  • Number of citations of the paper that reports this interaction (PubMedID 16901786)
  • 146
  • Data Source:
  • HPRD (in vitro)

USP28

TP53BP1

Description ubiquitin specific peptidase 28 tumor protein p53 binding protein 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alcohol consumption (drinks per week) ( 30643258)
  • Low density lipoprotein cholesterol levels ( 32154731)
  • PR interval ( 32439900)
  • Antibody level in response to infection ( 25758998)
  • Apolipoprotein A1 levels ( 32203549)
  • Cardiometabolic and hematological traits ( 27668658)
  • Eosinophil counts ( 32888494)
  • HDL cholesterol levels ( 32203549 30698716)
  • HDL cholesterol levels in current drinkers ( 30698716)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Hematocrit ( 32888494)
  • Hemoglobin ( 32888494)
  • Lipoprotein phospholipase A2 activity in cardiovascular disease ( 28753643)
  • Liver volume ( 34128465)
  • Lung cancer in ever smokers ( 28604730)
  • Mean corpuscular volume ( 32888494)
  • Triglyceride levels ( 30698716)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Triglycerides ( 27036123)
Interacting Genes 40 interacting genes: ATXN3L BAP1 CLSPN ESPL1 HIF1A JOSD1 KDM1A MAP3K1 MDC1 MTNR1A NSMCE2 OTUB1 OTUB2 PJA1 PLA2G2A PRKD1 RFFL SENP1 SENP8 STAM STAMBP SUMO2 TP53 TP53BP1 TRIM55 TRIM63 UBC UCHL1 UCHL3 UCHL5 USP14 USP15 USP20 USP21 USP33 USP4 USP5 USP51 USP7 USP8 59 interacting genes: ANKS1A ARAP1 ATM BCL6 BLM BRCA1 BRCA2 C10orf55 CCDC120 CCNB1 CDK1 CHEK1 CRB2 CREB5 DCLRE1A DCLRE1C DYNLL1 E2F1 EP300 GALNTL5 H2AC4 H2AX H4-16 H4C1 H4C14 HGS IFI16 KAT8 KDM1A KLHDC7B LIG4 MDC1 MEOX2 NCOA3 NEK1 NFKB1 NUDT16 OXER1 PARP1 PAXIP1 PCNT PITX1 POU6F2 PTEN RAD18 RAD50 RAD51 RBL1 RBL2 RELA SLC6A9 SPAG9 SUMO2 TFDP1 TLX3 TP53 UBAP2 USP28 VAC14
Entrez ID 57646 7158
HPRD ID 15632 05569
Ensembl ID ENSG00000048028 ENSG00000067369
Uniprot IDs B4E3L3 Q96RU2 A6NNK5 Q12888
PDB IDs 2LVA 2MUU 6H4H 6H4I 6HEH 6HEI 6HEJ 6HEK 1GZH 1KZY 1XNI 2G3R 2IG0 2LVM 2MWO 2MWP 3LGF 3LGL 3LH0 4CRI 4RG2 4X34 5ECG 5J26 5KGF 5Z78 5ZCJ 6CO1 6CO2 6IU7 6IUA 6MXX 6MXY 6MXZ 6MY0 6RML 6RMM 6UPT 6VA5 6VIP
Enriched GO Terms of Interacting Partners?
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