PAK5 and UXT

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		PAK5	UXT
Description		p21 (RAC1) activated kinase 5	ubiquitously expressed prefoldin like chaperone
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Cytosol Plasma Membrane Synapse	Chromatin Spindle Pole Nucleus Nucleoplasm Cytoplasm Centrosome Cytoskeleton
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity	Chromatin Binding Transcription Coregulator Activity Transcription Corepressor Activity Protein Binding Microtubule Binding Beta-tubulin Binding Actin Filament Binding
	Biological Process	Regulation Of Cell Growth Protein Phosphorylation Apoptotic Process Cytoskeleton Organization Signal Transduction Learning Memory Locomotory Behavior Cell Population Proliferation Cell Migration Intracellular Signal Transduction Regulation Of MAPK Cascade Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	Negative Regulation Of Transcription By RNA Polymerase II Microtubule Cytoskeleton Organization Regulation Of Transcription By RNA Polymerase II Apoptotic Process Centrosome Cycle Mitochondrion Transport Along Microtubule
Pathways		Activation of RAC1 CDC42 GTPase cycle RAC1 GTPase cycle RHOD GTPase cycle RHOH GTPase cycle	Transcriptional Regulation by E2F6
Drugs		Fostamatinib
Diseases
GWAS		Atopy ( 28927820) Plasma factor V levels in venous thrombosis (conditioned on rs6027) ( 31271701) Schizophrenia, bipolar disorder or recurrent major depressive disorder x sex interaction ( 34099189)
Interacting Genes		34 interacting genes: ARHGEF19 ARMC7 ATPAF2 BAD CARD9 CATSPER1 CCDC57 CCNG1 CDC42 CRBN CSNK1D DDX6 DNPEP EMD ENKD1 EXOSC1 FHL3 GCC1 INKA1 LENG1 LNX1 LZTS2 MYO15B NTAQ1 PDLIM7 PRPF31 PSMF1 PTPN21 RAC1 RHOJ SORBS3 TSGA10 TUBGCP4 UXT	29 interacting genes: APP AR CECR2 DYNLT1 GLE1 KRT31 KRT40 KRTAP1-3 KRTAP10-7 KRTAP10-8 KRTAP12-3 KRTAP5-7 KRTAP5-9 LRPPRC LSM1 MACROD1 MCPH1 MPP1 NBPF19 NOTCH2NLA PAK5 RCAN1 RUNX1 SIAH1 SVIL TRIM55 TRIM63 TXNIP VHL
Entrez ID		57144	8409
HPRD ID		06423	02209
Ensembl ID		ENSG00000101349	ENSG00000126756
Uniprot IDs		B0AZM9 Q9P286	Q9UBK9
PDB IDs		2F57
Enriched GO Terms of Interacting Partners?
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