UXT and MCPH1

  • Number of citations of the paper that reports this interaction (PubMedID 29150431)
  • 8
  • Data Source:
  • BioGRID (two hybrid)

UXT

MCPH1

Description ubiquitously expressed prefoldin like chaperone microcephalin 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alcoholic chronic pancreatitis ( 28754779)
  • Birth weight ( 31043758)
  • Carotid intima media thickness ( 30510157)
  • Carotid intima media thickness (mean) ( 31801372)
  • Cytomegalovirus antibody response ( 21993531)
  • Diastolic blood pressure ( 30224653)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Epirubicin-induced leukopenia ( 21799462)
  • Estimated glomerular filtration rate ( 31152163)
  • Gut microbiota relative abundance (Faecalibacterium) ( 33208821)
  • Heel bone mineral density ( 30598549)
  • Intraocular pressure ( 29785010)
  • Metabolite levels ( 23823483)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Venlafaxine response in generalised anxiety disorder (remitters vs non-remitters after 24 weeks) ( 28437668)
Interacting Genes 29 interacting genes: APP AR CECR2 DYNLT1 GLE1 KRT31 KRT40 KRTAP1-3 KRTAP10-7 KRTAP10-8 KRTAP12-3 KRTAP5-7 KRTAP5-9 LRPPRC LSM1 MACROD1 MCPH1 MPP1 NBPF19 NOTCH2NLA PAK5 RCAN1 RUNX1 SIAH1 SVIL TRIM55 TRIM63 TXNIP VHL 68 interacting genes: ABCC2 ACTG1 AKIP1 AKR7A2 ATM ATR B3GALT6 CCDC77 CCT5 CHEK1 COL1A1 COL27A1 COPB2 COPS3 CTSL DNAJA3 DNAJC19 EIF3F EIF4A2 EMG1 ENO1 FBLN1 FLNA GABARAPL2 HNRNPA2B1 HSPD1 KAT5 KDM1A LAMTOR5 LGALS3 MCM2 MCM5 MITD1 MRPL46 MT2A NCCRP1 NMI NR2F1 OBSL1 PHF11 PMVK POLD1 POLR2G PPA1 PPRC1 RACK1 RBM39 RSL24D1 RUVBL2 S100A16 SMARCB1 SMARCC2 SMOX SUPT6H TADA2A TAF1D THAP11 TPT1 TRAP1 TSEN54 UXT VIM WDR53 WDR61 WDR73 WDR75 WNT10B ZMIZ2
Entrez ID 8409 79648
HPRD ID 02209 06174
Ensembl ID ENSG00000126756 ENSG00000147316
Uniprot IDs Q9UBK9 Q8NEM0
PDB IDs 2WT8 3KTF 3PA6 3SHT 3SHV 3SZM 3T1N 3U3Z 7C5D
Enriched GO Terms of Interacting Partners?
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