RTN4 and NRXN1

RTN4

NRXN1

Description reticulon 4 neurexin 1
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Age at first sexual intercourse ( 34211149)
  • Body mass index ( 28892062)
  • Chromosomal aberration frequency (chromatid type) ( 31586183)
  • Chronotype ( 30696823)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Colorectal cancer x fine particulate matter exposure levels interaction ( 33338681)
  • Educational attainment ( 25201988)
  • General risk tolerance (MTAG) ( 30643258)
  • Isovolumetric relaxation time ( 28394258)
  • Lateral ventricle temporal horn volume ( 31530798)
  • Longevity ( 20834067)
  • Lung cancer in ever smokers ( 28604730)
  • Metabolite levels (HVA/MHPG ratio) ( 23319000)
  • Morning person ( 30696823)
  • Nicotine dependence symptom count ( 25555482)
  • Personality dimensions ( 20691247)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Recurrent major depressive disorder ( 34099189)
  • Refractive astigmatism ( 25367360)
  • Response to zileuton treatment in asthma (FEV1 change interaction) ( 26031901)
  • Severe gingival inflammation ( 28459102)
  • Smoking initiation ( 33082346)
  • Systolic blood pressure ( 30224653 30578418)
  • Temperament ( 22832960)
  • Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931)
  • Triglyceride levels ( 32203549)
  • Word spelling ( 30741946)
Interacting Genes 55 interacting genes: BAIAP2 BCL2 BCL2L1 BDKRB1 CCR4 CERT1 CGREF1 CHMP6 CHRM4 CLN8 CNTNAP1 CRMP1 CYSLTR2 DRD2 ERBB2 ERBB3 ERBB4 F2RL1 FXR2 GLP1R GPR35 HLA-DPB1 HTR2C IPP LAMA4 LINC01554 LMNA LRCH4 LRPAP1 MBP NAPA NR4A1 NRXN1 NSD1 OGT PLEKHF2 POT1 PPP1R21 PRR13 RAB33A RPS27 RTN3 RTN4IP1 RTN4R SNX1 SNX15 SPG21 STON1 SYT16 TERF1 TUBA4A UQCRC1 UQCRC2 WWP1 ZFYVE21 29 interacting genes: AFDN APBA1 APBA2 ATP13A2 CASK MACF1 MYO16 NLGN1 NLGN2 NLGN3 NXPH1 NXPH2 NXPH3 PDZD2 RPH3A RTN4 SDCBP2 SIPA1L1 SYT1 SYT13 SYT2 SYT4 SYT5 SYT6 SYT7 SYT9 SYTL1 SYTL2 SYTL3
Entrez ID 57142 9378
HPRD ID 07259 11858
Ensembl ID ENSG00000115310 ENSG00000179915
Uniprot IDs Q9NQC3 A0A0D9SEM5 A0A0D9SEQ7 A0A1D5RMU6 E7EQN4 E7ERL8 H0Y568 H7BYC7 P58400 Q9ULB1
PDB IDs 2G31 2JV5 3B3Q 5Z8Y 6NID
Enriched GO Terms of Interacting Partners?
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