NRXN1 and CASK

  • Number of citations of the paper that reports this interaction (PubMedID 8786425)
  • 163
  • Data Source:
  • HPRD (in vitro, two hybrid)

NRXN1

CASK

Description neurexin 1 calcium/calmodulin dependent serine protein kinase
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Age at first sexual intercourse ( 34211149)
  • Body mass index ( 28892062)
  • Chromosomal aberration frequency (chromatid type) ( 31586183)
  • Chronotype ( 30696823)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Colorectal cancer x fine particulate matter exposure levels interaction ( 33338681)
  • Educational attainment ( 25201988)
  • General risk tolerance (MTAG) ( 30643258)
  • Isovolumetric relaxation time ( 28394258)
  • Lateral ventricle temporal horn volume ( 31530798)
  • Longevity ( 20834067)
  • Lung cancer in ever smokers ( 28604730)
  • Metabolite levels (HVA/MHPG ratio) ( 23319000)
  • Morning person ( 30696823)
  • Nicotine dependence symptom count ( 25555482)
  • Personality dimensions ( 20691247)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Recurrent major depressive disorder ( 34099189)
  • Refractive astigmatism ( 25367360)
  • Response to zileuton treatment in asthma (FEV1 change interaction) ( 26031901)
  • Severe gingival inflammation ( 28459102)
  • Smoking initiation ( 33082346)
  • Systolic blood pressure ( 30224653 30578418)
  • Temperament ( 22832960)
  • Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931)
  • Triglyceride levels ( 32203549)
  • Word spelling ( 30741946)
Interacting Genes 29 interacting genes: AFDN APBA1 APBA2 ATP13A2 CASK MACF1 MYO16 NLGN1 NLGN2 NLGN3 NXPH1 NXPH2 NXPH3 PDZD2 RPH3A RTN4 SDCBP2 SIPA1L1 SYT1 SYT13 SYT2 SYT4 SYT5 SYT6 SYT7 SYT9 SYTL1 SYTL2 SYTL3 87 interacting genes: AKAP9 APBA1 ATP2B4 BNIP3L C20orf85 CADM1 CASKIN1 CDK9 CNTNAP2 CNTNAP4 DDX54 DLG1 DLG4 DUSP3 ELL2 EPB41 EPS8 ERBIN F11R FCHSD2 FMR1 GCNT3 GLS2 GRIK2 GRIN2A GTSE1 HGS ID1 IL15RA IL18 KCNA4 KCNJ12 KCNJ2 KCNJ4 KIF2A KLC4 LIN7A LIN7B MAPRE1 MAPRE2 MARK2 MARS1 MED1 MLLT6 MLX NDEL1 NPHS1 NRXN1 NRXN2 NRXN3 NTN4 P2RX7 PARD3B PARD6G PCBP2 PCM1 PKP2 PLK2 PPP4R3A PRC1 PRKCI PRKD2 PRKN PRPF3 PTGS2 RAB3A RBBP6 RBM10 RBM14 RBM5 RPA2 RPH3A SDC1 SDC2 SDC3 SDC4 SF3B2 SH2D4A SLAIN2 SRPK2 TANC1 TBR1 TRIM22 TSPYL2 WHRN WNT7B YWHAE
Entrez ID 9378 8573
HPRD ID 11858 02164
Ensembl ID ENSG00000179915 ENSG00000147044
Uniprot IDs A0A0D9SEM5 A0A0D9SEQ7 A0A1D5RMU6 E7EQN4 E7ERL8 H0Y568 H7BYC7 P58400 Q9ULB1 A0A2R8Y6F8 A0A2R8YE77 A0A7I2RJN6 O14936
PDB IDs 3B3Q 5Z8Y 6NID 1KGD 1KWA 1ZL8 3C0G 3C0H 3C0I 3MFR 3MFS 3MFT 3MFU 3TAC 6KMH
Enriched GO Terms of Interacting Partners?
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