PSEN1 and HERPUD1

  • Number of citations of the paper that reports this interaction (PubMedID 11799129)
  • 27
  • Data Source:
  • HPRD (in vivo)

PSEN1

HERPUD1

Description presenilin 1 homocysteine inducible ER protein with ubiquitin like domain 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Aspartate aminotransferase levels ( 33547301)
  • Cardiovascular risk factors ( 20838585)
  • Coronary artery disease ( 29212778)
  • Diisocyanate-induced asthma ( 25918132)
  • HDL cholesterol ( 20031564 23505323 24886709)
  • HDL Cholesterol in HIV-infection ( 25884002)
  • HDL cholesterol levels ( 26763881 30698716)
  • HDL cholesterol levels in current drinkers ( 30698716)
  • HDL cholesterol levels in HIV infection ( 33109212)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • High density lipoprotein cholesterol levels ( 29403010 33339817)
  • Hip circumference adjusted for BMI ( 34021172)
  • Hypo-HDL-cholesterolemia ( 31087446)
  • LDL cholesterol levels ( 30698716)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Low density lipoprotein cholesterol levels ( 33339817)
  • Low HDL-cholesterol levels ( 31910446)
  • Metabolic syndrome ( 20694148)
  • Metabolite levels ( 23823483)
  • Serum metabolite levels ( 33031748)
  • Total cholesterol levels ( 29403010 33339817)
  • Triglyceride levels ( 29403010 33339817)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
Interacting Genes 98 interacting genes: ACTN1 AP1M2 APBA1 APH1A APH1B APOE APP BACE1 BCL2 BCL2L1 CASP1 CASP3 CASP4 CASP6 CASP7 CASP8 CDH1 CDK5 CFL1 CIB1 CKB CTNNA1 CTNNB1 CTNND1 CTNND2 CYP2C18 CYP2C8 DCT DLL1 DOCK3 ECSIT EFHD1 EFNB2 ENSA EPB41L3 ERN1 ETFA FBXL12 FBXW7 FGF13 FLNA FLNB GAPDH GCDH GDI1 GFAP GSK3B GSTZ1 HERPUD1 HMGB1 ICAM5 ITSN2 JUP KANK2 KCNIP3 KCNIP4 LRRC74A MAPK9 MAPT METTL2B MTCH1 NCSTN NOS3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 OXCT1 PDCD4 PIK3R1 PKP4 PRAM1 PRDX2 PRKACA PRKCZ PSENEN PSMA5 PSMB1 RAB11A RAB3A RAD23A RBSN RHEB RMDN3 RNF32 RYR2 SCAF11 SCN1A SLC10A6 SNUPN ST13 STAMBPL1 TCF7L2 TDP2 TUBA1B UBQLN1 UMPS YME1L1 20 interacting genes: AMFR APP ARHGDIA C5AR2 CCR2 CD3D CD58 CHRM2 EWSR1 F2RL1 IMPA2 PSEN1 RPA2 SH3RF1 STARD9 TOLLIP UBQLN2 USP7 VCP XRCC6
Entrez ID 5663 9709
HPRD ID 00087 07456
Ensembl ID ENSG00000080815 ENSG00000051108
Uniprot IDs A0A024R6A3 A0A0S2Z4D2 P49768 A4UAE9 Q15011 Q53FP9
PDB IDs 2KR6 4UIS 5A63 5FN2 5FN3 5FN4 5FN5 6IDF 6IYC 6LQG 6LR4 7C9I 7D8X 1WGD
Enriched GO Terms of Interacting Partners?
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