PRPSAP2 and PRPSAP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PRPSAP2	PRPSAP1
Description		phosphoribosyl pyrophosphate synthetase associated protein 2	phosphoribosyl pyrophosphate synthetase associated protein 1
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GO Annotations	Cellular Component	Ribose Phosphate Diphosphokinase Complex Cytoplasm	Ribose Phosphate Diphosphokinase Complex Cytoplasm
	Molecular Function	Magnesium Ion Binding Ribose Phosphate Diphosphokinase Activity Enzyme Inhibitor Activity Protein Binding Identical Protein Binding	Magnesium Ion Binding Ribose Phosphate Diphosphokinase Activity Enzyme Inhibitor Activity Protein Binding Identical Protein Binding
	Biological Process	5-phosphoribose 1-diphosphate Biosynthetic Process Nucleobase-containing Compound Metabolic Process Purine Nucleotide Biosynthetic Process Nucleoside Metabolic Process Negative Regulation Of Catalytic Activity	5-phosphoribose 1-diphosphate Biosynthetic Process Nucleobase-containing Compound Metabolic Process Purine Nucleotide Biosynthetic Process Negative Regulation Of Catalytic Activity
Pathways
Drugs
Diseases
GWAS		Mean spheric corpuscular volume ( 32888494) Pancreatic cancer ( 20686608)	High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) High-grade serous ovarian cancer ( 31469419) Nontraumatic osteonecrosis of the femoral head ( 32701715) Red cell distribution width ( 32888494) Reticulocyte count ( 32888494) Urate levels ( 23263486)
Interacting Genes		6 interacting genes: APP ENDOV PRPS1 PRPS2 PRPSAP1 TEX11	9 interacting genes: CAPN7 DDX19B MAGOHB MAPK1 PLEKHF2 PRPS1 PRPS2 PRPSAP2 UBE2I
Entrez ID		5636	5635
HPRD ID		04789	03151
Ensembl ID		ENSG00000141127	ENSG00000161542
Uniprot IDs		A0A024QYY3 O60256	B4DP31 Q14558
PDB IDs		2JI4	2C4K
Enriched GO Terms of Interacting Partners?
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