PRPSAP2 and PRPS2

Number of citations of the paper that reports this interaction (PubMedID 26186194)
524

Data Source:
BioGRID (affinity chromatography technology, biochemical, affinity chromatography technology, two hybrid)

		PRPSAP2	PRPS2
Description		phosphoribosyl pyrophosphate synthetase associated protein 2	phosphoribosyl pyrophosphate synthetase 2
Image			No pdb structure
GO Annotations	Cellular Component	Ribose Phosphate Diphosphokinase Complex Cytoplasm	Ribose Phosphate Diphosphokinase Complex Cytoplasm
	Molecular Function	Magnesium Ion Binding Ribose Phosphate Diphosphokinase Activity Enzyme Inhibitor Activity Protein Binding Identical Protein Binding	Magnesium Ion Binding Ribose Phosphate Diphosphokinase Activity Protein Binding ATP Binding Kinase Activity Identical Protein Binding Protein Homodimerization Activity
	Biological Process	5-phosphoribose 1-diphosphate Biosynthetic Process Nucleobase-containing Compound Metabolic Process Purine Nucleotide Biosynthetic Process Nucleoside Metabolic Process Negative Regulation Of Catalytic Activity	5-phosphoribose 1-diphosphate Biosynthetic Process Nucleobase-containing Compound Metabolic Process Purine Nucleotide Biosynthetic Process Nucleoside Metabolic Process Ribonucleoside Monophosphate Biosynthetic Process Phosphorylation
Pathways			5-Phosphoribose 1-diphosphate biosynthesis
Drugs
Diseases
GWAS		Mean spheric corpuscular volume ( 32888494) Pancreatic cancer ( 20686608)	Metabolite levels ( 23823483) Systemic lupus erythematosus ( 26606652 33272962)
Interacting Genes		6 interacting genes: APP ENDOV PRPS1 PRPS2 PRPSAP1 TEX11	4 interacting genes: NOTCH2NLA NTAQ1 PRPSAP1 PRPSAP2
Entrez ID		5636	5634
HPRD ID		04789	02414
Ensembl ID		ENSG00000141127	ENSG00000101911
Uniprot IDs		A0A024QYY3 O60256	A0A140VK41 P11908
PDB IDs		2JI4
Enriched GO Terms of Interacting Partners?
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