PRPSAP1 and PRPSAP2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PRPSAP1	PRPSAP2
Description		phosphoribosyl pyrophosphate synthetase associated protein 1	phosphoribosyl pyrophosphate synthetase associated protein 2
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GO Annotations	Cellular Component	Ribose Phosphate Diphosphokinase Complex Cytoplasm	Ribose Phosphate Diphosphokinase Complex Cytoplasm
	Molecular Function	Magnesium Ion Binding Ribose Phosphate Diphosphokinase Activity Enzyme Inhibitor Activity Protein Binding Identical Protein Binding	Magnesium Ion Binding Ribose Phosphate Diphosphokinase Activity Enzyme Inhibitor Activity Protein Binding Identical Protein Binding
	Biological Process	5-phosphoribose 1-diphosphate Biosynthetic Process Nucleobase-containing Compound Metabolic Process Purine Nucleotide Biosynthetic Process Negative Regulation Of Catalytic Activity	5-phosphoribose 1-diphosphate Biosynthetic Process Nucleobase-containing Compound Metabolic Process Purine Nucleotide Biosynthetic Process Nucleoside Metabolic Process Negative Regulation Of Catalytic Activity
Pathways
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) High-grade serous ovarian cancer ( 31469419) Nontraumatic osteonecrosis of the femoral head ( 32701715) Red cell distribution width ( 32888494) Reticulocyte count ( 32888494) Urate levels ( 23263486)	Mean spheric corpuscular volume ( 32888494) Pancreatic cancer ( 20686608)
Interacting Genes		9 interacting genes: CAPN7 DDX19B MAGOHB MAPK1 PLEKHF2 PRPS1 PRPS2 PRPSAP2 UBE2I	6 interacting genes: APP ENDOV PRPS1 PRPS2 PRPSAP1 TEX11
Entrez ID		5635	5636
HPRD ID		03151	04789
Ensembl ID		ENSG00000161542	ENSG00000141127
Uniprot IDs		B4DP31 Q14558	A0A024QYY3 O60256
PDB IDs		2C4K	2JI4
Enriched GO Terms of Interacting Partners?
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