PRPS2 and PRPSAP2

Number of citations of the paper that reports this interaction (PubMedID 26186194)
524

Data Source:
BioGRID (affinity chromatography technology, biochemical, affinity chromatography technology, two hybrid)

		PRPS2	PRPSAP2
Description		phosphoribosyl pyrophosphate synthetase 2	phosphoribosyl pyrophosphate synthetase associated protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Ribose Phosphate Diphosphokinase Complex Cytoplasm	Ribose Phosphate Diphosphokinase Complex Cytoplasm
	Molecular Function	Magnesium Ion Binding Ribose Phosphate Diphosphokinase Activity Protein Binding ATP Binding Kinase Activity Identical Protein Binding Protein Homodimerization Activity	Magnesium Ion Binding Ribose Phosphate Diphosphokinase Activity Enzyme Inhibitor Activity Protein Binding Identical Protein Binding
	Biological Process	5-phosphoribose 1-diphosphate Biosynthetic Process Nucleobase-containing Compound Metabolic Process Purine Nucleotide Biosynthetic Process Nucleoside Metabolic Process Ribonucleoside Monophosphate Biosynthetic Process Phosphorylation	5-phosphoribose 1-diphosphate Biosynthetic Process Nucleobase-containing Compound Metabolic Process Purine Nucleotide Biosynthetic Process Nucleoside Metabolic Process Negative Regulation Of Catalytic Activity
Pathways		5-Phosphoribose 1-diphosphate biosynthesis
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Systemic lupus erythematosus ( 26606652 33272962)	Mean spheric corpuscular volume ( 32888494) Pancreatic cancer ( 20686608)
Interacting Genes		4 interacting genes: NOTCH2NLA NTAQ1 PRPSAP1 PRPSAP2	6 interacting genes: APP ENDOV PRPS1 PRPS2 PRPSAP1 TEX11
Entrez ID		5634	5636
HPRD ID		02414	04789
Ensembl ID		ENSG00000101911	ENSG00000141127
Uniprot IDs		A0A140VK41 P11908	A0A024QYY3 O60256
PDB IDs			2JI4
Enriched GO Terms of Interacting Partners?
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