THAP12 and TACC1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		THAP12	TACC1
Description		THAP domain containing 12	transforming acidic coiled-coil containing protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Cytoplasm Microtubule Organizing Center Cytosol Membrane Midbody
	Molecular Function	DNA Binding Protein Binding Metal Ion Binding Protein Dimerization Activity	Protein Binding Nuclear Receptor Binding Estrogen Receptor Binding Nuclear Receptor Coactivator Activity Glucocorticoid Receptor Binding Retinoic Acid Receptor Binding Peroxisome Proliferator Activated Receptor Binding Retinoid X Receptor Binding Thyroid Hormone Receptor Binding
	Biological Process	Signal Transduction Negative Regulation Of Cell Population Proliferation	Microtubule Cytoskeleton Organization Mitotic Spindle Organization Cell Population Proliferation Cerebral Cortex Development Positive Regulation Of Transcription, DNA-templated Cell Division
Pathways
Drugs
Diseases
GWAS		Asthma ( 31959851) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction ( 34099189)	Blond vs. brown/black hair color ( 30531825) Chronic mountain sickness ( 31417607) Midgestational circulating levels of PBDEs ( 28235828)
Interacting Genes		10 interacting genes: DDX58 DNAJC3 EIF2AK2 EIF2S1 KIAA1958 MAPKAPK3 STK4 TACC1 TP53 ZNF526	20 interacting genes: AURKA AURKB BTRC ERCC4 FAM50B HTT ITSN2 KAT2A KDM1A LSM7 MEMO1 SH2D4A SNRPG STX5 TDRD7 THAP12 THRA YEATS4 ZFHX3 ZNF48
Entrez ID		5612	6867
HPRD ID		09567	10391
Ensembl ID		ENSG00000137492	ENSG00000147526
Uniprot IDs		A0A140VJQ7 O43422	E7EVI4 O75410 Q5HYH0
PDB IDs
Enriched GO Terms of Interacting Partners?
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