TACC1 and FAM50B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TACC1	FAM50B
Description		transforming acidic coiled-coil containing protein 1	family with sequence similarity 50 member B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Microtubule Organizing Center Cytosol Membrane Midbody	Nucleus Nucleoplasm Midbody Intercellular Bridge
	Molecular Function	Protein Binding Nuclear Receptor Binding Estrogen Receptor Binding Nuclear Receptor Coactivator Activity Glucocorticoid Receptor Binding Retinoic Acid Receptor Binding Peroxisome Proliferator Activated Receptor Binding Retinoid X Receptor Binding Thyroid Hormone Receptor Binding	Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Spindle Organization Cell Population Proliferation Cerebral Cortex Development Positive Regulation Of Transcription, DNA-templated Cell Division	Chromatin Organization
Pathways
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Chronic mountain sickness ( 31417607) Midgestational circulating levels of PBDEs ( 28235828)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin) ( 23648065)
Interacting Genes		20 interacting genes: AURKA AURKB BTRC ERCC4 FAM50B HTT ITSN2 KAT2A KDM1A LSM7 MEMO1 SH2D4A SNRPG STX5 TDRD7 THAP12 THRA YEATS4 ZFHX3 ZNF48	49 interacting genes: ACTN2 ADRA1A BICD2 CARD9 CCDC136 CCDC57 CCDC85B CCDC89 CCNC CDR2 DEUP1 FSD2 GFAP GMCL1 GOLGA2 GRIPAP1 HAP1 HOOK2 IKZF1 KASH5 KPNA3 KPNA4 KRT31 KRT34 LDOC1 LZTS1 LZTS2 MID1 MID2 MLH1 NUTF2 PAX6 PDE4DIP PIBF1 PSMB1 RABEP1 TACC1 TBC1D1 TFIP11 TRAF2 TRIM14 TRIM37 TRIM54 UBL5 VAC14 VPS52 WBP4 ZMYND12 ZRANB1
Entrez ID		6867	26240
HPRD ID		10391	16883
Ensembl ID		ENSG00000147526	ENSG00000145945
Uniprot IDs		E7EVI4 O75410 Q5HYH0	A0A024QZY3 Q9Y247
PDB IDs
Enriched GO Terms of Interacting Partners?
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