PRKCI and PARD3

  • Number of citations of the paper that reports this interaction (PubMedID 14676191)
  • 60
  • Data Source:
  • HPRD (in vivo)

PRKCI

PARD3

Description protein kinase C iota par-3 family cell polarity regulator
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute lymphoblastic leukemia (childhood) ( 19684603)
  • Adult body size ( 32376654)
  • Apolipoprotein A1 levels ( 32203549)
  • Brain morphology (MOSTest) ( 32665545)
  • Corneal astigmatism ( 30306274)
  • Emphysema-related traits ( 20709820)
  • Estimated glomerular filtration rate ( 31015462)
  • Gut microbiota relative abundance (Sutterella) ( 33208821)
  • HDL cholesterol levels ( 32203549)
  • Hip circumference adjusted for BMI ( 28552196)
  • Liver enzyme levels (gamma-glutamyl transferase) ( 33972514)
  • Lung function (FEV1/FVC) ( 30804560)
  • Major depressive disorder ( 21621269)
  • Parkinson's disease progression (composite) ( 33111402)
  • Schizophrenia ( 21682944)
Interacting Genes 53 interacting genes: ADAP1 ANXA1 APP BAD CASK CASP8 CCNT1 CDC42 CDK7 CHUK CTBP1 FABP4 FCGR3A FRS2 FRS3 GAPDH HRAS IKBKG IL1RAP IRAK1 MAP2K1 MAP2K5 MAPT MARK4 MBP MEOX2 NACC1 NFKBIA PARD3 PARD6A PARD6B PARD6G PCM1 PDPK1 PIK3CA PNMA1 RAB2A RAB4A RAC1 RBM14 RHOQ RPA2 SMG1 SMURF1 SQSTM1 SRC TSC22D1 TTR UBC USP20 VHL YWHAH YWHAZ 33 interacting genes: ACE2 AP1B1 CDC42 DYNLL1 F11R HNF1B INSC LIMK2 MAP3K8 NECTIN1 NECTIN3 PARD6A PARD6B PARD6G PATJ PLCB1 PLCB3 PNMA1 PRKCG PRKCI SMAD1 SMAD2 SMAD3 SMAD4 SMAD7 STK11 TIAM1 TIAM2 TTN YWHAB YWHAG YWHAH YWHAZ
Entrez ID 5584 56288
HPRD ID 02105 05994
Ensembl ID ENSG00000163558 ENSG00000148498
Uniprot IDs P41743 Q8TEW0
PDB IDs 1VD2 1WMH 1ZRZ 3A8W 3A8X 3ZH8 5LI1 5LI9 5LIH 6ILZ 2KOM
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?