PRKCI and FABP4

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		PRKCI	FABP4
Description		protein kinase C iota	fatty acid binding protein 4
Image
GO Annotations	Cellular Component	Golgi Membrane Nucleus Nucleoplasm Endosome Cytosol Plasma Membrane Bicellular Tight Junction Microtubule Cytoskeleton Apical Plasma Membrane Cell Leading Edge Schmidt-Lanterman Incisure Intercellular Bridge Extracellular Exosome Schaffer Collateral - CA1 Synapse Glutamatergic Synapse	Nucleus Cytoplasm Lipid Droplet Cytosol Extracellular Exosome
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Kinase C Activity Calcium-dependent Protein Kinase C Activity Protein Binding ATP Binding Phospholipid Binding Metal Ion Binding Protein Serine Kinase Activity	Long-chain Fatty Acid Transporter Activity Fatty Acid Binding Long-chain Fatty Acid Binding Hormone Receptor Binding
	Biological Process	Protein Phosphorylation Protein Targeting To Membrane Cytoskeleton Organization Actin Filament Organization Positive Regulation Of Neuron Projection Development Vesicle-mediated Transport Cell Migration Peptidyl-serine Phosphorylation Cellular Response To Insulin Stimulus Negative Regulation Of Glial Cell Apoptotic Process Establishment Of Apical/basal Cell Polarity Intracellular Signal Transduction Eye Photoreceptor Cell Development Negative Regulation Of Apoptotic Process Negative Regulation Of Neuron Apoptotic Process Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Cell-cell Junction Organization Positive Regulation Of Notch Signaling Pathway Positive Regulation Of Glucose Import Secretion Golgi Vesicle Budding Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Glial Cell Proliferation Membrane Organization Response To Interleukin-1 Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Endothelial Cell Apoptotic Process	Negative Regulation Of Protein Kinase Activity Response To Bacterium Long-chain Fatty Acid Transport Cholesterol Homeostasis Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Inflammatory Response White Fat Cell Differentiation Brown Fat Cell Differentiation Cellular Response To Lithium Ion Cellular Response To Tumor Necrosis Factor Positive Regulation Of Cold-induced Thermogenesis
Pathways		Pre-NOTCH Transcription and Translation p75NTR recruits signalling complexes Tight junction interactions	Triglyceride catabolism Triglyceride catabolism Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs		Tamoxifen Bisindolylmaleimide I Fostamatinib
Diseases
GWAS		Aspartate aminotransferase levels ( 33547301) Microalbuminuria ( 31511532) Prostate cancer ( 25939597) Urinary albumin excretion ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189 31511532)	Blood protein levels ( 30072576) Metabolite levels ( 23823483) Ovarian cancer ( 23535730) Visceral fat ( 22589738)
Interacting Genes		53 interacting genes: ADAP1 ANXA1 APP BAD CASK CASP8 CCNT1 CDC42 CDK7 CHUK CTBP1 FABP4 FCGR3A FRS2 FRS3 GAPDH HRAS IKBKG IL1RAP IRAK1 MAP2K1 MAP2K5 MAPT MARK4 MBP MEOX2 NACC1 NFKBIA PARD3 PARD6A PARD6B PARD6G PCM1 PDPK1 PIK3CA PNMA1 RAB2A RAB4A RAC1 RBM14 RHOQ RPA2 SMG1 SMURF1 SQSTM1 SRC TSC22D1 TTR UBC USP20 VHL YWHAH YWHAZ	8 interacting genes: ACP1 ACTB CHD3 INSR LIPE PRKCI VIM ZBED1
Entrez ID		5584	2167
HPRD ID		02105	02698
Ensembl ID		ENSG00000163558	ENSG00000170323
Uniprot IDs		P41743	E7DVW4 P15090
PDB IDs		1VD2 1WMH 1ZRZ 3A8W 3A8X 3ZH8 5LI1 5LI9 5LIH 6ILZ	1TOU 1TOW 2HNX 2NNQ 3FR2 3FR4 3FR5 3P6C 3P6D 3P6E 3P6F 3P6G 3P6H 3Q6L 3RZY 4NNS 4NNT 5D45 5D47 5D48 5D4A 5EDB 5EDC 5HZ6 5HZ8 5Y0F 5Y0G 5Y0X 5Y12 5Y13 6AYL 6LJS 6LJT 6LJU 6LJV 6LJW 6LJX
Enriched GO Terms of Interacting Partners?
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