PARD3 and LIMK2

  • Number of citations of the paper that reports this interaction (PubMedID 16505165)
  • 30
  • Data Source:
  • HPRD (in vitro, in vivo)

PARD3

LIMK2

Description par-3 family cell polarity regulator LIM domain kinase 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute lymphoblastic leukemia (childhood) ( 19684603)
  • Adult body size ( 32376654)
  • Apolipoprotein A1 levels ( 32203549)
  • Brain morphology (MOSTest) ( 32665545)
  • Corneal astigmatism ( 30306274)
  • Emphysema-related traits ( 20709820)
  • Estimated glomerular filtration rate ( 31015462)
  • Gut microbiota relative abundance (Sutterella) ( 33208821)
  • HDL cholesterol levels ( 32203549)
  • Hip circumference adjusted for BMI ( 28552196)
  • Liver enzyme levels (gamma-glutamyl transferase) ( 33972514)
  • Lung function (FEV1/FVC) ( 30804560)
  • Major depressive disorder ( 21621269)
  • Parkinson's disease progression (composite) ( 33111402)
  • Schizophrenia ( 21682944)
Interacting Genes 33 interacting genes: ACE2 AP1B1 CDC42 DYNLL1 F11R HNF1B INSC LIMK2 MAP3K8 NECTIN1 NECTIN3 PARD6A PARD6B PARD6G PATJ PLCB1 PLCB3 PNMA1 PRKCG PRKCI SMAD1 SMAD2 SMAD3 SMAD4 SMAD7 STK11 TIAM1 TIAM2 TTN YWHAB YWHAG YWHAH YWHAZ 13 interacting genes: CDC42BPA CFL1 FBXO7 FCGR2A GSN H1-1 HIPK3 LIMK1 MBP NF1 PARD3 ROCK1 RPS6KA1
Entrez ID 56288 3985
HPRD ID 05994 03585
Ensembl ID ENSG00000148498 ENSG00000182541
Uniprot IDs Q8TEW0 A0A024R1H6 A0A024R1M2 P53671
PDB IDs 2KOM 1X6A 4TPT 5NXD
Enriched GO Terms of Interacting Partners?
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