PRKCE and NUMB

  • Number of citations of the paper that reports this interaction (PubMedID 17203073)
  • 95
  • Data Source:
  • HPRD (in vitro)

PRKCE

NUMB

Description protein kinase C epsilon NUMB endocytic adaptor protein
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Bipolar disorder with mood-incongruent psychosis ( 23092984)
  • Coronary artery calcification ( 17903303)
  • Hemoglobin ( 32888494)
  • Macular thickness ( 30535121)
  • Multisite chronic pain ( 33830993 31194737)
  • White matter hyperintensity volume x hypertension interaction (2df) ( 33293549)
Interacting Genes 59 interacting genes: ACTA1 ACTC1 ADAP1 AFAP1 AKAP9 ATF2 BRAF BTK CFTR CHAT CNN1 COPB1 COPB2 DSP EGFR ELAVL1 FYN GAD1 GAD2 GJA1 GNA12 GNA13 GRIN1 GRIN2D GRM5 H1-1 HK2 IKBKB ITGB1 ITGB2 KRT1 KRT18 MAP4K4 MAPK1 MAPK3 MAPT MARK2 MYH2 NANOG NUMB OPRD1 PDLIM5 PDPK1 PECAM1 PIK3CB PPP1R14A PRKD1 RACK1 RAD9A RAF1 RASGRP3 RPS6KB2 SLC25A4 SLC4A3 SNCA SRC TIAM1 TRPV1 VDAC1 36 interacting genes: AP2A1 AP2A2 APP DPYSL2 EAF1 EGFR EPS15 FBXO7 FRS3 IRS1 ITCH ITGB2 ITGB3 ITGB5 L1CAM LNX1 LNX2 MAPK8IP2 MDM2 NEDD4 NOTCH1 OLIG1 PALS1 PDZK1IP1 PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCZ PTEN RPL3 SIAH1 SPANXN2 TERF2
Entrez ID 5581 8650
HPRD ID 01500 04767
Ensembl ID ENSG00000171132 ENSG00000133961
Uniprot IDs L7RTI5 Q02156 A0A024R681 A0A024R684 A0A024R6C4 A0A024R6F4 P49757
PDB IDs 2WH0 5LIH 5NJJ 5NJK
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?