NUMB and ITGB3

  • Number of citations of the paper that reports this interaction (PubMedID 12606711)
  • 126
  • Data Source:
  • HPRD (in vitro)

NUMB

ITGB3

Description NUMB endocytic adaptor protein integrin subunit beta 3
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Bipolar disorder with mood-incongruent psychosis ( 23092984)
  • Coronary artery calcification ( 17903303)
  • Hemoglobin ( 32888494)
  • Macular thickness ( 30535121)
  • Multisite chronic pain ( 33830993 31194737)
  • White matter hyperintensity volume x hypertension interaction (2df) ( 33293549)
  • Body mass index ( 25673413)
  • Brain morphology (MOSTest) ( 32665545)
  • Chromosomal aberration frequency (chromosome type) in genotoxic compound exposure ( 31586183)
  • Eosinophil counts ( 32888494)
  • Eosinophil percentage of white cells ( 32888494)
  • Height ( 33713608)
  • High chromosomal aberration frequency (chromosome type) ( 31586183)
  • Hip circumference adjusted for BMI ( 34021172)
  • Mean platelet volume ( 27863252)
  • Medication use (thyroid preparations) ( 31015401)
  • Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)
Interacting Genes 36 interacting genes: AP2A1 AP2A2 APP DPYSL2 EAF1 EGFR EPS15 FBXO7 FRS3 IRS1 ITCH ITGB2 ITGB3 ITGB5 L1CAM LNX1 LNX2 MAPK8IP2 MDM2 NEDD4 NOTCH1 OLIG1 PALS1 PDZK1IP1 PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCZ PTEN RPL3 SIAH1 SPANXN2 TERF2 49 interacting genes: AKT1 ANGPTL3 APP CAPN1 CD36 CDK1 COL1A2 DAB1 DAB2 DOK1 EPS8 FBLN2 FGA FGFR1 FGG FLNA FLNB FN1 GRIA2 HRAS ILK ITGA2B ITGA5 ITGAV ITGB3BP KDR MAPK3 NID1 NUMB P2RY2 P4HB PDGFRA PDGFRB PDK1 PDPK1 PECAM1 PLA2G2A PLA2G4A PTK2 PTK2B PXN SHC1 SRC TGM2 THBS1 THY1 TLN1 TNS2 VTN
Entrez ID 8650 3690
HPRD ID 04767 01428
Ensembl ID ENSG00000133961 ENSG00000259207
Uniprot IDs A0A024R681 A0A024R684 A0A024R6C4 A0A024R6F4 P49757 P05106
PDB IDs 5NJJ 5NJK 1JV2 1KUP 1KUZ 1L5G 1M1X 1M8O 1MIZ 1MK7 1MK9 1RN0 1S4X 1TYE 1U8C 2INI 2K9J 2KNC 2KV9 2L1C 2L91 2LJD 2LJE 2LJF 2MTP 2N9Y 2Q6W 2RMZ 2RN0 2VC2 2VDK 2VDL 2VDM 2VDN 2VDO 2VDP 2VDQ 2VDR 3FCS 3FCU 3IJE 3NID 3NIF 3NIG 3T3M 3T3P 3ZDX 3ZDY 3ZDZ 3ZE0 3ZE1 3ZE2 4CAK 4G1E 4G1M 4MMX 4MMY 4MMZ 4O02 4Z7N 4Z7O 4Z7Q 5HDB 6AVQ 6AVR 6AVU 6BXB 6BXF 6BXJ 6CKB 6MK0 6MSL 6MSU 6NAJ 6V4P
Enriched GO Terms of Interacting Partners?
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