VAC14 and FAM50B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		VAC14	FAM50B
Description		VAC14 component of PIKFYVE complex	family with sequence similarity 50 member B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extrinsic Component Of Vacuolar Membrane Endoplasmic Reticulum Cytosol Endosome Membrane Early Endosome Membrane Late Endosome Membrane Intracellular Membrane-bounded Organelle PAS Complex	Nucleus Nucleoplasm Midbody Intercellular Bridge
	Molecular Function	Protein Binding Signaling Receptor Activity Identical Protein Binding	Protein Binding
	Biological Process	Phosphatidylinositol Biosynthetic Process Signal Transduction Positive Regulation Of Kinase Activity	Chromatin Organization
Pathways		Synthesis of PIPs at the Golgi membrane Synthesis of PIPs at the Golgi membrane Synthesis of PIPs at the early endosome membrane Synthesis of PIPs at the early endosome membrane Synthesis of PIPs at the late endosome membrane Synthesis of PIPs at the late endosome membrane
Drugs
Diseases
GWAS		Diffuse cutaneous systemic sclerosis ( 29293537) Docetaxel-induced peripheral neuropathy in metastatic castrate-resistant prostate cancer ( 27143689) High density lipoprotein cholesterol levels ( 28548082) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Malaria ( 31844061) Pulse pressure ( 28135244)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin) ( 23648065)
Interacting Genes		108 interacting genes: ABHD11 ACSS1 AMT APP ARID5A ASB13 BCL2L1 BHLHE40 C11orf54 C19orf54 C2CD6 C4orf33 CASP1 CCDC103 CD209 CDRT4 CNTN2 COL8A1 CRK CRYBA1 CRYBA2 DDAH2 EEF1AKMT3 EHHADH EIF2S1 EIF6 FAM50B FIG4 FNDC3B GABPB2 GALT GINS3 GLIS2 GNB1 GTF3C2 HDHD3 HNF1B HNRNPLL INTS11 JMJD7 KEAP1 KHDC1 KRBOX5 KRT82 KRTAP15-1 KRTAP19-3 KRTAP19-5 KRTAP19-7 KRTAP6-1 KRTAP6-2 KYAT1 LASP1 LINC00518 LPAL2 MBLAC1 MEOX2 METTL15 MGAT5B MPPED2 MTMR9 MVP MYOZ1 NDUFAB1 NGB NOS1 NTAQ1 OIT3 OTOS PBLD PCMTD2 PDE4DIP PELI1 PHF1 PHYKPL PIKFYVE PPP2CA PPP6C PRADC1 PRR13 PRR20A PRR20B PRR20C PRR20D PRR20E RBFOX2 RHBDL1 RHOXF2 RIPPLY1 RNASEH2C RSKR SIGLEC5 SMUG1 SNF8 SPRYD7 SRPK2 TCEANC TEX37 TP53BP1 TRIM55 TRIM63 UFSP1 VENTX VHLL WDR83 WRAP53 ZBTB49 ZCWPW1 ZNF34	49 interacting genes: ACTN2 ADRA1A BICD2 CARD9 CCDC136 CCDC57 CCDC85B CCDC89 CCNC CDR2 DEUP1 FSD2 GFAP GMCL1 GOLGA2 GRIPAP1 HAP1 HOOK2 IKZF1 KASH5 KPNA3 KPNA4 KRT31 KRT34 LDOC1 LZTS1 LZTS2 MID1 MID2 MLH1 NUTF2 PAX6 PDE4DIP PIBF1 PSMB1 RABEP1 TACC1 TBC1D1 TFIP11 TRAF2 TRIM14 TRIM37 TRIM54 UBL5 VAC14 VPS52 WBP4 ZMYND12 ZRANB1
Entrez ID		55697	26240
HPRD ID		07660	16883
Ensembl ID		ENSG00000103043	ENSG00000145945
Uniprot IDs		Q08AM6	A0A024QZY3 Q9Y247
PDB IDs
Enriched GO Terms of Interacting Partners?
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