FAM50B and GFAP

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		FAM50B	GFAP
Description		family with sequence similarity 50 member B	glial fibrillary acidic protein
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Midbody Intercellular Bridge	Cytoplasm Lysosome Cytosol Intermediate Filament Cell Body Intermediate Filament Cytoskeleton Astrocyte End-foot Cytoplasmic Side Of Lysosomal Membrane
	Molecular Function	Protein Binding	Integrin Binding Structural Constituent Of Cytoskeleton Protein Binding Kinase Binding Identical Protein Binding
	Biological Process	Chromatin Organization	Intracellular Protein Transport Response To Wounding Gene Expression Positive Regulation Of Schwann Cell Proliferation Negative Regulation Of Neuron Projection Development Astrocyte Development Extracellular Matrix Organization Neuron Projection Regeneration Regulation Of Protein-containing Complex Assembly Intermediate Filament Organization Regulation Of Neurotransmitter Uptake Bergmann Glial Cell Differentiation Long-term Synaptic Potentiation D-aspartate Import Across Plasma Membrane Regulation Of Chaperone-mediated Autophagy
Pathways			Nuclear signaling by ERBB4 Chaperone Mediated Autophagy
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin) ( 23648065)	Asthma ( 31619474) Cognitive function ( 25644384) Craniofacial microsomia ( 26853712)
Interacting Genes		49 interacting genes: ACTN2 ADRA1A BICD2 CARD9 CCDC136 CCDC57 CCDC85B CCDC89 CCNC CDR2 DEUP1 FSD2 GFAP GMCL1 GOLGA2 GRIPAP1 HAP1 HOOK2 IKZF1 KASH5 KPNA3 KPNA4 KRT31 KRT34 LDOC1 LZTS1 LZTS2 MID1 MID2 MLH1 NUTF2 PAX6 PDE4DIP PIBF1 PSMB1 RABEP1 TACC1 TBC1D1 TFIP11 TRAF2 TRIM14 TRIM37 TRIM54 UBL5 VAC14 VPS52 WBP4 ZMYND12 ZRANB1	83 interacting genes: ABI2 AKT1 APP AURKB BIRC2 CAMK2A CARD10 CCDC57 CDC37 CDK1 CEP76 CFAP206 CRYAB CT55 CWF19L2 ENKD1 EPM2AIP1 FAM50B FXR1 FXR2 GOLGA2 GRAP2 HGS HOMEZ IKBKG KIAA0408 KRT13 KRT15 KRT19 KRT27 KRT31 KRT39 LENG1 LGALS14 LMO2 MAPK9 MEN1 MOS MYBPHL MYO15B NEFL NEK6 NFKBID NTAQ1 NXF1 PDLIM1 PDLIM7 PDZK1 PIAS2 PIH1D2 POM121 PPP1R16B PPP1R18 PRKACA PRKCA PRKCG PSEN1 PSEN2 RIBC2 ROCK1 RORA S100A1 S100B SH3YL1 SMARCA2 SMARCB1 SRC STAT1 TBC1D21 TBC1D22B TFIP11 TLE5 TP53BP2 TRIM27 TSC1 TUBGCP4 UBASH3A UBE3A VIM YES1 ZC2HC1C ZNF655 ZNF774
Entrez ID		26240	2670
HPRD ID		16883	00675
Ensembl ID		ENSG00000145945	ENSG00000131095
Uniprot IDs		A0A024QZY3 Q9Y247	P14136
PDB IDs			6A9P
Enriched GO Terms of Interacting Partners?
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