CSGALNACT2 and SYNE4

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		CSGALNACT2	SYNE4
Description		chondroitin sulfate N-acetylgalactosaminyltransferase 2	spectrin repeat containing nuclear envelope family member 4
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Membrane Integral Component Of Golgi Membrane Golgi Cisterna Membrane	Integral Component Of Nuclear Outer Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex
	Molecular Function	Protein Binding Acetylgalactosaminyltransferase Activity Metal Ion Binding Glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase Activity Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase Activity	Protein Binding
	Biological Process	Proteoglycan Biosynthetic Process Chondroitin Sulfate Biosynthetic Process Chondroitin Sulfate Proteoglycan Biosynthetic Process Dermatan Sulfate Proteoglycan Biosynthetic Process Dermatan Sulfate Proteoglycan Biosynthetic Process, Polysaccharide Chain Biosynthetic Process Chondroitin Sulfate Proteoglycan Biosynthetic Process, Polysaccharide Chain Biosynthetic Process	Establishment Of Epithelial Cell Apical/basal Polarity
Pathways		Chondroitin sulfate biosynthesis
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Central corneal thickness ( 32528159) Hip circumference adjusted for BMI ( 34021172) Hirschsprung disease ( 25310821) Multiple sclerosis ( 24076602)
Interacting Genes		20 interacting genes: ARL13B ATP1B4 BSND CLDN2 CREB3L1 CYB5R3 FCGR2A GPR152 HSD17B11 LMNA MFSD14B MUC1 RETREG3 SLC35E3 SSMEM1 SYNE4 SYT1 TMEM143 TMEM52B UBE2I	57 interacting genes: ABT1 ADIPOQ BRICD5 C3orf52 CD47 CEP19 CLDN19 CLDN7 CLDN8 CLEC7A CMTM5 CSGALNACT2 CSNK2B CXCL9 DEFB121 ECE2 EDDM3B EMP1 ENTPD3 FAM241B FATE1 GADD45A GSK3B IGFBP5 ITM2B KLHL12 KLRG1 KTN1 MALL MARCHF2 NAGK OCLN OLFM4 OSTCP1 PAQR5 PLPP6 RIPPLY2 RPS6KA6 SEC22A SEC23B SENP2 SFTPC SLN SMCO4 TCEA2 TMEM115 TMEM140 TMEM147 TMEM182 TMEM248 TMPRSS4 TRIM69 TSPAN15 VTI1B WDR62 ZNF250 ZNF648
Entrez ID		55454	163183
HPRD ID		11348	08776
Ensembl ID		ENSG00000169826	ENSG00000181392
Uniprot IDs		A0A0S2Z5F5 A0A0S2Z5F9 A0A0S2Z5K4 Q8N6G5	Q8N205
PDB IDs			6R16 6WMD
Enriched GO Terms of Interacting Partners?
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