TMEM176A and SCD5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TMEM176A	SCD5
Description		transmembrane protein 176A	stearoyl-CoA desaturase 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	Stearoyl-CoA 9-desaturase Activity Iron Ion Binding Oxidoreductase Activity
	Biological Process	Negative Regulation Of Dendritic Cell Differentiation	Unsaturated Fatty Acid Biosynthetic Process Monounsaturated Fatty Acid Biosynthetic Process
Pathways			Fatty acyl-CoA biosynthesis EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs
Diseases
GWAS		Forced expiratory volume in 1 second (occupational environmental exposures interaction) ( 25979521) HDL cholesterol ( 24097068) HDL cholesterol levels ( 28334899) Height ( 20881960 23563607) Metabolite levels ( 23823483) Serum alkaline phosphatase levels ( 33547301) Serum metabolite concentrations in chronic kidney disease ( 29545352) Waist circumference adjusted for body mass index ( 34021172)	Basophil count ( 32888494) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Erosive tooth wear (severe vs non-severe) ( 29898447) Granulocyte count ( 27863252) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Lymphocyte counts ( 32888494 27863252) Monocyte count ( 29403010 32888494) Monocyte percentage of white cells ( 32888494) Neutrophil percentage of granulocytes ( 27863252) Neutrophil percentage of white cells ( 32888494) Sum eosinophil basophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Type 2 diabetes ( 30054458 30297969) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683) White blood cell count ( 29403010 32888494) White blood cell count (basophil) ( 27863252)
Interacting Genes		17 interacting genes: CD79A CERS4 CHPF2 GOLM1 HIVEP1 KCNK5 MFSD14B MTIF3 RETREG3 RIDA SCD5 SGPL1 TGM2 TIMMDC1 TMEM176B TMX2 VKORC1	1 interacting genes: TMEM176A
Entrez ID		55365	79966
HPRD ID		13635	09756
Ensembl ID		ENSG00000002933	ENSG00000145284
Uniprot IDs		A0A090N8H6 Q96HP8	Q86SK9 Q86UC8
PDB IDs
Enriched GO Terms of Interacting Partners?
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