POLD1 and MCPH1

  • Number of citations of the paper that reports this interaction (PubMedID 29150431)
  • 8
  • Data Source:
  • BioGRID (two hybrid)

POLD1

MCPH1

Description DNA polymerase delta 1, catalytic subunit microcephalin 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Dental caries (decayed, missing and filled tooth surfaces) ( 31533690)
  • Obesity-related traits ( 23251661)
  • Alcoholic chronic pancreatitis ( 28754779)
  • Birth weight ( 31043758)
  • Carotid intima media thickness ( 30510157)
  • Carotid intima media thickness (mean) ( 31801372)
  • Cytomegalovirus antibody response ( 21993531)
  • Diastolic blood pressure ( 30224653)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Epirubicin-induced leukopenia ( 21799462)
  • Estimated glomerular filtration rate ( 31152163)
  • Gut microbiota relative abundance (Faecalibacterium) ( 33208821)
  • Heel bone mineral density ( 30598549)
  • Intraocular pressure ( 29785010)
  • Metabolite levels ( 23823483)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Venlafaxine response in generalised anxiety disorder (remitters vs non-remitters after 24 weeks) ( 28437668)
Interacting Genes 23 interacting genes: ADAMTSL4 ASXL1 ATR CCND3 CCNE1 CDK2 CDK4 CEP126 CHGB GINS4 LASP1 MCPH1 PCNA POLA1 POLD2 POLD3 POLD4 SUMO2 TREX2 TRIM55 WRNIP1 XRCC5 YPEL3 68 interacting genes: ABCC2 ACTG1 AKIP1 AKR7A2 ATM ATR B3GALT6 CCDC77 CCT5 CHEK1 COL1A1 COL27A1 COPB2 COPS3 CTSL DNAJA3 DNAJC19 EIF3F EIF4A2 EMG1 ENO1 FBLN1 FLNA GABARAPL2 HNRNPA2B1 HSPD1 KAT5 KDM1A LAMTOR5 LGALS3 MCM2 MCM5 MITD1 MRPL46 MT2A NCCRP1 NMI NR2F1 OBSL1 PHF11 PMVK POLD1 POLR2G PPA1 PPRC1 RACK1 RBM39 RSL24D1 RUVBL2 S100A16 SMARCB1 SMARCC2 SMOX SUPT6H TADA2A TAF1D THAP11 TPT1 TRAP1 TSEN54 UXT VIM WDR53 WDR61 WDR73 WDR75 WNT10B ZMIZ2
Entrez ID 5424 79648
HPRD ID 08882 06174
Ensembl ID ENSG00000062822 ENSG00000147316
Uniprot IDs A0A024R4F4 A0A087WYJ2 M0R2B7 P28340 Q308M6 Q59FA0 Q8NEM0
PDB IDs 6S1M 6S1N 6S1O 6TNY 6TNZ 2WT8 3KTF 3PA6 3SHT 3SHV 3SZM 3T1N 3U3Z 7C5D
Enriched GO Terms of Interacting Partners?
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