MCPH1 and FLNA

  • Number of citations of the paper that reports this interaction (PubMedID 29150431)
  • 8
  • Data Source:
  • BioGRID (two hybrid)

MCPH1

FLNA

Description microcephalin 1 filamin A
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alcoholic chronic pancreatitis ( 28754779)
  • Birth weight ( 31043758)
  • Carotid intima media thickness ( 30510157)
  • Carotid intima media thickness (mean) ( 31801372)
  • Cytomegalovirus antibody response ( 21993531)
  • Diastolic blood pressure ( 30224653)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Epirubicin-induced leukopenia ( 21799462)
  • Estimated glomerular filtration rate ( 31152163)
  • Gut microbiota relative abundance (Faecalibacterium) ( 33208821)
  • Heel bone mineral density ( 30598549)
  • Intraocular pressure ( 29785010)
  • Metabolite levels ( 23823483)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Venlafaxine response in generalised anxiety disorder (remitters vs non-remitters after 24 weeks) ( 28437668)
  • Immature fraction of reticulocytes ( 32888494)
  • White blood cell count ( 32888494)
Interacting Genes 68 interacting genes: ABCC2 ACTG1 AKIP1 AKR7A2 ATM ATR B3GALT6 CCDC77 CCT5 CHEK1 COL1A1 COL27A1 COPB2 COPS3 CTSL DNAJA3 DNAJC19 EIF3F EIF4A2 EMG1 ENO1 FBLN1 FLNA GABARAPL2 HNRNPA2B1 HSPD1 KAT5 KDM1A LAMTOR5 LGALS3 MCM2 MCM5 MITD1 MRPL46 MT2A NCCRP1 NMI NR2F1 OBSL1 PHF11 PMVK POLD1 POLR2G PPA1 PPRC1 RACK1 RBM39 RSL24D1 RUVBL2 S100A16 SMARCB1 SMARCC2 SMOX SUPT6H TADA2A TAF1D THAP11 TPT1 TRAP1 TSEN54 UXT VIM WDR53 WDR61 WDR73 WDR75 WNT10B ZMIZ2 100 interacting genes: ADAMTSL4 APC AR ARHGAP24 ARRB1 ARRB2 ASB2 BRCA1 BRCA2 CALCR CAMK2G CASR CAV1 CCNB1 CDC42 CEACAM1 CMIP DCN DDIT4L DRD1 DRD2 DRD3 DUX4 ERBB3 F3 FABP1 FBLIM1 FILIP1 FLNB FURIN GP1BA GRIK1 GRIK3 GRM4 GRM5 GRM7 GRM8 HHLA3 HMGB2 HNRNPD HSPA6 HSPB7 ITGB1 ITGB3 ITGB5 ITGB6 ITGB7 KCNE4 KCNJ2 KLHL12 LGALS14 LMNA MAP2K4 MAPK14 MCPH1 MTDH MTNR1A MTNR1B MYOT MYOZ1 NLGN3 NPHP1 OPRM1 PAK1 PCBP2 PELO PHOSPHO2 PLEKHF2 PRKCA PSEN1 PSEN2 PTEN RAC1 RALA REL RFLNA RHOA SELE SH2B3 SHBG SIGLEC10 SIRPA SMAD3 SMAD5 SPANXD SRC SUMO2 SVIL SYNPO2 TCF4 TLR10 TNIP2 TP73 TRAF2 TRIM55 TRIO TTN USP19 VHL YWHAG
Entrez ID 79648 2316
HPRD ID 06174 02060
Ensembl ID ENSG00000147316 ENSG00000196924
Uniprot IDs Q8NEM0 P21333 Q60FE5 Q6NXF2
PDB IDs 2WT8 3KTF 3PA6 3SHT 3SHV 3SZM 3T1N 3U3Z 7C5D 2AAV 2BP3 2BRQ 2J3S 2JF1 2K3T 2K7P 2K7Q 2MTP 2W0P 2WFN 3CNK 3HOC 3HOP 3HOR 3ISW 3RGH 4M9P 4P3W 5XR1 6D8C 6EW1
Enriched GO Terms of Interacting Partners?
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