PMCH and MCHR1

Number of citations of the paper that reports this interaction (PubMedID 11839762)
2

Data Source:
HPRD (in vitro)

		PMCH	MCHR1
Description		pro-melanin concentrating hormone	melanin concentrating hormone receptor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Synapse	Plasma Membrane Integral Component Of Plasma Membrane Cilium Neuron Projection Ciliary Membrane Non-motile Cilium
	Molecular Function	Melanin-concentrating Hormone Activity Type 1 Melanin-concentrating Hormone Receptor Binding	G Protein-coupled Receptor Activity Signaling Receptor Binding Protein C-terminus Binding Neuropeptide Receptor Activity Melanin-concentrating Hormone Receptor Activity Peptide Binding Hormone Binding Neuropeptide Binding
	Biological Process	Neuropeptide Signaling Pathway Chemical Synaptic Transmission Spermatogenesis Behavior Feeding Behavior Cell Differentiation	Generation Of Precursor Metabolites And Energy Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Neuropeptide Signaling Pathway Feeding Behavior Positive Regulation Of Calcium Ion Transport
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events G alpha (i) signalling events	Peptide ligand-binding receptors G alpha (q) signalling events G alpha (i) signalling events BBSome-mediated cargo-targeting to cilium
Drugs			Haloperidol
Diseases
GWAS		Adventurousness ( 30643258) Brain morphology (MOSTest) ( 32665545) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Height ( 19893584) Number of sexual partners ( 30643258)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Body mass index ( 26426971) Feeling worry ( 29500382) Large artery stroke ( 28265093) Neurociticism ( 29500382) Refractive error ( 32231278) Schizophrenia ( 28991256)
Interacting Genes		10 interacting genes: CPE FURIN MCHR1 MCHR2 NPY PCSK1 PCSK2 PCSK5 PCSK6 PCSK7	3 interacting genes: EP300 PMCH ZMYND19
Entrez ID		5367	2847
HPRD ID		01459	11874
Ensembl ID		ENSG00000183395	ENSG00000128285
Uniprot IDs		P20382	Q99705
PDB IDs
Enriched GO Terms of Interacting Partners?
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