PLA2G4A and CASP1

  • Number of citations of the paper that reports this interaction (PubMedID 9875225)
  • 7
  • Data Source:
  • HPRD (in vitro)

PLA2G4A

CASP1

Description phospholipase A2 group IVA caspase 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood urea nitrogen levels ( 31152163)
  • Body size at age 10 ( 32376654)
  • Crohn's disease ( 26192919)
  • Estimated glomerular filtration rate ( 31152163)
  • Generalized epilepsy ( 22949513)
  • Hip circumference adjusted for BMI ( 28552196)
  • Hyperinsulinemia in less-fat diet ( 30327367)
  • Hyperinsulinemia x saturated fatty acids interaction ( 30327367)
  • Inflammatory bowel disease ( 26192919)
  • Knee osteoarthritis ( 18471798)
  • Non-del(5q) myelodysplastic syndromes ( 31738830)
  • Uterine fibroid size (maximum volume) ( 30196971)
  • Zinc levels ( 26025379)
  • Hip circumference adjusted for BMI ( 28552196)
Interacting Genes 24 interacting genes: ANXA2 BORCS6 CAP1 CASP1 CASP3 CASP4 ITGA2B ITGB3 JAK1 KAT5 MAPK1 MAPK14 MAPKAPK5 MKNK1 NCF1 PLA2G5 PRKCA RELA RPS6KA5 SHBG SIRT2 UBXN1 VIM XAGE1B 45 interacting genes: AR ATN1 ATXN3 BCAP31 BCL2L1 BID CARD16 CARD17 CARD8 CASP10 CASP14 CASP8 CAST CDK11B DRD2 EGFR FGF2 HTT HUWE1 IL18 IL1A IL1B IL33 IL37 LMNA MAPT NEDD4 NFE2L2 NLRC4 NLRP1 NOD1 PAK1 PARP1 PLA2G4A PLA2G4B PRKN PSEN1 PSEN2 PYCARD RIPK2 RNF31 SERPINB9 TFAP2A TIRAP VAC14
Entrez ID 5321 834
HPRD ID 08986 00977
Ensembl ID ENSG00000116711 ENSG00000137752
Uniprot IDs B4DZI4 P47712 A8K249 A8K257 P29466
PDB IDs 1BCI 1CJY 1RLW 1BMQ 1IBC 1ICE 1RWK 1RWM 1RWN 1RWO 1RWP 1RWV 1RWW 1RWX 1SC1 1SC3 1SC4 2FQQ 2H48 2H4W 2H4Y 2H51 2H54 2HBQ 2HBR 2HBY 2HBZ 3D6F 3D6H 3D6M 3E4C 3NS7 5FNA 5MMV 5MTK 6BZ9 6F6R 6KN0 6PZP 6VIE 7KEU
Enriched GO Terms of Interacting Partners?
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