PLA2G2A and USP8

  • Number of citations of the paper that reports this interaction (PubMedID 22118674)
  • 143
  • Data Source:
  • BioGRID (enzymatic study)

PLA2G2A

USP8

Description phospholipase A2 group IIA ubiquitin specific peptidase 8
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood protein levels ( 30072576 29875488)
  • Group IIA secretory phospholipase A2 levels in individuals with elevated hsCRP ( 31070471)
  • Immunoglobulin light chain (AL) amyloidosis ( 28025584)
  • Ankylosing spondylitis ( 30946743)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Heel bone mineral density ( 30598549)
  • Mean reticulocyte volume ( 32888494)
  • Monocyte percentage of white cells ( 32888494)
Interacting Genes 27 interacting genes: ALOX12 BAG6 CEP70 CRMP1 DCN ITGAV ITGB3 JOSD2 PLA2G1B PLA2R1 SENP6 SENP8 SUZ12 UCHL1 UCHL3 UCHL5 USP15 USP2 USP20 USP28 USP4 USP47 USP5 USP7 USP8 VCAN VIM 43 interacting genes: BACE1 BIRC6 CFLAR CHMP1A CHMP1B CHMP2A CHMP2B CHMP4C CHMP7 DNAJB6 EPS15 GNAL GRAP2 GRB2 H2AC20 H2BC21 KIF23 NBR1 NTRK2 PJA1 PLA2G2A RASGRF1 RNF41 SEC31A SHANK1 SHANK3 SLBP SNCA SPP1 SQSTM1 SRC STAM STAM2 TRIM54 TRIM55 TRIM63 UBC USP15 USP21 USP28 YWHAG YWHAQ YWHAZ
Entrez ID 5320 9101
HPRD ID 01397 04405
Ensembl ID ENSG00000188257 ENSG00000138592
Uniprot IDs A0A024RA96 P14555 A0A024R5S4 A8K8N5 P40818
PDB IDs 1AYP 1BBC 1DB4 1DB5 1DCY 1J1A 1KQU 1KVO 1N28 1N29 1POD 1POE 2GNY 3U8B 3U8D 3U8H 3U8I 5G3N 1WHB 2A9U 2GFO 2GWF 3N3K 6F09
Enriched GO Terms of Interacting Partners?
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