USP8 and EPS15

  • Number of citations of the paper that reports this interaction (PubMedID 16771824)
  • 48
  • Data Source:
  • BioGRID (enzymatic study)

USP8

EPS15

Description ubiquitin specific peptidase 8 epidermal growth factor receptor pathway substrate 15
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Ankylosing spondylitis ( 30946743)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Heel bone mineral density ( 30598549)
  • Mean reticulocyte volume ( 32888494)
  • Monocyte percentage of white cells ( 32888494)
Interacting Genes 43 interacting genes: BACE1 BIRC6 CFLAR CHMP1A CHMP1B CHMP2A CHMP2B CHMP4C CHMP7 DNAJB6 EPS15 GNAL GRAP2 GRB2 H2AC20 H2BC21 KIF23 NBR1 NTRK2 PJA1 PLA2G2A RASGRF1 RNF41 SEC31A SHANK1 SHANK3 SLBP SNCA SPP1 SQSTM1 SRC STAM STAM2 TRIM54 TRIM55 TRIM63 UBC USP15 USP21 USP28 YWHAG YWHAQ YWHAZ 50 interacting genes: AGFG1 AGFG2 AP1G1 AP2A1 AP2A2 CLINT1 CORO7 CRK DNM1 DNM2 EGFR ELF3 EPN1 EPN2 FCHO1 FCHO2 GRB2 HGS ITSN1 LAPTM5 MAPK14 MOB4 MTNR1A NAGPA NEDD4 NUMB NUMBL PPT1 PRKN REPS2 RNF11 SCAMP1 SGIP1 SNAP91 SPART SPOPL STAM2 STAMBP STON2 SYNJ1 TFAP2A UBB UBC UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2H UBQLN1 USP8
Entrez ID 9101 2060
HPRD ID 04405 08968
Ensembl ID ENSG00000138592 ENSG00000085832
Uniprot IDs A0A024R5S4 A8K8N5 P40818 B7Z240 P42566
PDB IDs 1WHB 2A9U 2GFO 2GWF 3N3K 6F09 1C07 1EH2 1F8H 1FF1 2IV9 2JXC 4RH5 4RH9 4RHG 4S0G 5AWT 5AWU 5JP2
Enriched GO Terms of Interacting Partners?
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