PDK1 and PIK3CA

  • Number of citations of the paper that reports this interaction (PubMedID 21041639)
  • 54
  • Data Source:
  • BioGRID (protein complementation assay)

PDK1

PIK3CA

Description pyruvate dehydrogenase kinase 1 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood protein levels ( 28240269)
  • Erectile dysfunction in type 1 diabetes ( 22704111)
  • Fasting plasma glucose ( 25187374)
Interacting Genes 15 interacting genes: AKT1 COL6A1 DLAT FGFR1 ITGB3 KAT2B LAMTOR5 PDHA1 PDK2 PIK3CA RPS6KB1 SGK1 USP4 XRCC6 YWHAQ 78 interacting genes: ACOT8 ADAP1 AKT1 ALCAM AMBP APLP2 APPL1 ARAF ATP5IF1 ATR BEX1 BEX2 CCND2 CRIP1 CSF1R CYTH2 CYTH3 DDX5 DNAJB6 EGFR FANCC FASLG FBP2 FTL GABRB1 GALNT12 GLIS2 GNAQ GRIN2B HRAS IL13RA2 IL24 IL3 IRS2 IRS4 ITIH1 KRAS LCK LYPLA1 MAP2K1 MAP3K9 MRAS MYC NEDD4L NEDD9 NRAS PDGFRA PDGFRB PDK1 PIK3R1 PIK3R3 PRKCD PRKCI PSMC3IP PTPN11 RASD2 RASGRP3 RELA RHOC RPS20 RPS6KB1 SFRP4 SGK1 SH3KBP1 SMAD2 SMAD3 SNX9 SQSTM1 STAT1 STK11 THRSP TICAM1 TMOD1 TNFSF13 TRA2B UFD1 UMPS VARS2
Entrez ID 5163 5290
HPRD ID 03954 01382
Ensembl ID ENSG00000152256 ENSG00000121879
Uniprot IDs B7Z7N6 Q15118 P42336 Q4LE51
PDB IDs 2Q8F 2Q8G 2Q8H 2ENQ 2RD0 3HHM 3HIZ 3ZIM 4JPS 4L1B 4L23 4L2Y 4OVU 4OVV 4TUU 4TV3 4WAF 4YKN 4ZOP 5DXH 5DXT 5FI4 5ITD 5SW8 5SWG 5SWO 5SWP 5SWR 5SWT 5SX8 5SX9 5SXA 5SXB 5SXC 5SXD 5SXE 5SXF 5SXI 5SXJ 5SXK 5UBR 5UK8 5UKJ 5UL1 5XGH 5XGI 5XGJ 6GVF 6GVG 6GVH 6GVI 6NCT 6OAC 6PYS 6VO7 7K6M 7K6N 7K6O 7K71
Enriched GO Terms of Interacting Partners?
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