NCKIPSD and CPNE2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		NCKIPSD	CPNE2
Description		NCK interacting protein with SH3 domain	copine 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament	Nucleus Cytoplasm Plasma Membrane Extracellular Exosome
	Molecular Function	Protein Binding Cytoskeletal Protein Binding Myosin Binding SH3 Domain Binding Arp2/3 Complex Binding	Protein Binding Calcium-dependent Phospholipid Binding Metal Ion Binding
	Biological Process	Endocytosis Cytoskeleton Organization Positive Regulation Of Neuron Projection Development	Cellular Response To Calcium Ion
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Anorexia nervosa ( 31308545) Blood protein levels ( 28240269) Body shape index ( 34021172) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Intelligence (MTAG) ( 29326435) Myocardial infarction ( 33532862) Parkinson's disease ( 28892059) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172)
Interacting Genes		42 interacting genes: ABI2 ARHGEF7 BAIAP2 CCDC187 CPNE2 CYSLTR2 DIAPH2 DIAPH3 DLG4 DMRTB1 ENKD1 FASLG GAS7 GRB2 HSPB1 ITGB1 KHDRBS1 LGALS4 MAPK3 MED25 NCK1 NCK2 PIN1 PKP2 POLR3C PRPF31 PSMD9 PSORS1C2 RBM22 RBP7 RXFP3 SHANK3 SNRPC SORBS3 STAC TSEN54 VEZF1 WAS WASL YWHAG ZBTB47 ZC2HC1C	28 interacting genes: ACTB ANXA7 BCOR CDKN1A CT55 EFHC2 GBP7 IKBKG KATNBL1 LNX1 MEI4 MEOX2 MYCBP NCKIPSD PDCD6 PICK1 PPP5C RDX REL SKIL SORBS3 TCF4 TERF2IP THAP4 TRIM27 UBA3 UBE2M UBE2O
Entrez ID		51517	221184
HPRD ID		09450	05015
Ensembl ID		ENSG00000213672	ENSG00000140848
Uniprot IDs		Q9NZQ3	Q96FN4
PDB IDs		6DEC 6DED 6DEE
Enriched GO Terms of Interacting Partners?
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