NCKIPSD and DIAPH2

Number of citations of the paper that reports this interaction (PubMedID 11509578)
29

Data Source:
HPRD (in vivo, in vitro)

		NCKIPSD	DIAPH2
Description		NCK interacting protein with SH3 domain	diaphanous related formin 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament	Nucleolus Early Endosome Endoplasmic Reticulum Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Cytoskeletal Protein Binding Myosin Binding SH3 Domain Binding Arp2/3 Complex Binding	Actin Binding Signaling Receptor Binding Small GTPase Binding
	Biological Process	Endocytosis Cytoskeleton Organization Positive Regulation Of Neuron Projection Development	Actin Filament Organization Female Gamete Generation Oogenesis
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis	RHOF GTPase cycle
Drugs
Diseases
GWAS		Anorexia nervosa ( 31308545) Blood protein levels ( 28240269) Body shape index ( 34021172) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Intelligence (MTAG) ( 29326435) Myocardial infarction ( 33532862) Parkinson's disease ( 28892059) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172)
Interacting Genes		42 interacting genes: ABI2 ARHGEF7 BAIAP2 CCDC187 CPNE2 CYSLTR2 DIAPH2 DIAPH3 DLG4 DMRTB1 ENKD1 FASLG GAS7 GRB2 HSPB1 ITGB1 KHDRBS1 LGALS4 MAPK3 MED25 NCK1 NCK2 PIN1 PKP2 POLR3C PRPF31 PSMD9 PSORS1C2 RBM22 RBP7 RXFP3 SHANK3 SNRPC SORBS3 STAC TSEN54 VEZF1 WAS WASL YWHAG ZBTB47 ZC2HC1C	6 interacting genes: APBB1 CDC42 CENPA NCKIPSD RHOD TCERG1
Entrez ID		51517	1730
HPRD ID		09450	02117
Ensembl ID		ENSG00000213672	ENSG00000147202
Uniprot IDs		Q9NZQ3	O60879
PDB IDs		6DEC 6DED 6DEE
Enriched GO Terms of Interacting Partners?
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