ANKFY1 and RHOD

Number of citations of the paper that reports this interaction (PubMedID 24102721)
14

Data Source:
BioGRID (two hybrid)

		ANKFY1	RHOD
Description		ankyrin repeat and FYVE domain containing 1	ras homolog family member D
Image		No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Endosome Early Endosome Cytosol Endosome Membrane Membrane Intracellular Membrane-bounded Organelle Macropinosome Extracellular Exosome	Golgi Membrane Mitochondrial Outer Membrane Early Endosome Cytosol Cytoskeleton Plasma Membrane Cell Cortex Endosome Membrane Cytoplasmic Vesicle Cell Projection
	Molecular Function	Protein Binding Small GTPase Binding Metal Ion Binding Phosphatidylinositol Phosphate Binding	GTPase Activity Guanyl-nucleotide Exchange Factor Activity GTP Binding Protein Kinase Binding
	Biological Process	Endocytosis Endosomal Transport Endosomal Vesicle Fusion Retrograde Transport, Endosome To Golgi Positive Regulation Of Pinocytosis Golgi To Lysosome Transport	Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Rho Protein Signal Transduction Regulation Of Cell Shape Cell Migration Lamellipodium Assembly Positive Regulation Of Cell Migration Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Cell Adhesion Focal Adhesion Assembly Regulation Of Catalytic Activity Actin Filament Bundle Assembly Regulation Of Small GTPase Mediated Signal Transduction
Pathways		RHOD GTPase cycle	RHO GTPases Activate Formins RHOD GTPase cycle
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30578418) Functional impairment in major depressive disorder, bipolar disorder and schizophrenia ( 24039173) Hematocrit ( 32888494) Refractive error ( 32231278) Schizophrenia x sex interaction ( 34099189)	Height ( 20881960 25282103) Hip circumference adjusted for BMI ( 34021172) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		5 interacting genes: CLK1 RAB5A RHOD RHOF SRPK2	13 interacting genes: ACVR1 ADCK5 ADRB2 ANKFY1 BMPR1B DIAPH2 HRAS IHH PLXNA1 SMAD2 SMAD4 SMURF2 TGFBR1
Entrez ID		51479	29984
HPRD ID		09717	05776
Ensembl ID		ENSG00000185722	ENSG00000173156
Uniprot IDs		B3KPZ0 Q9P2R3	E9PIG5 O00212
PDB IDs			2J1L
Enriched GO Terms of Interacting Partners?
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