RHOD and PLXNA1

Number of citations of the paper that reports this interaction (PubMedID 11784792)
56

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		RHOD	PLXNA1
Description		ras homolog family member D	plexin A1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Mitochondrial Outer Membrane Early Endosome Cytosol Cytoskeleton Plasma Membrane Cell Cortex Endosome Membrane Cytoplasmic Vesicle Cell Projection	Semaphorin Receptor Complex Nucleoplasm Cytosol Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome
	Molecular Function	GTPase Activity Guanyl-nucleotide Exchange Factor Activity GTP Binding Protein Kinase Binding	Semaphorin Receptor Activity Signaling Receptor Activity
	Biological Process	Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Rho Protein Signal Transduction Regulation Of Cell Shape Cell Migration Lamellipodium Assembly Positive Regulation Of Cell Migration Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Cell Adhesion Focal Adhesion Assembly Regulation Of Catalytic Activity Actin Filament Bundle Assembly Regulation Of Small GTPase Mediated Signal Transduction	Negative Regulation Of Cell Adhesion Multicellular Organism Development Regulation Of Cell Shape Regulation Of Smooth Muscle Cell Migration Regulation Of Cell Migration Regulation Of GTPase Activity Positive Regulation Of Axonogenesis Dichotomous Subdivision Of Terminal Units Involved In Salivary Gland Branching Semaphorin-plexin Signaling Pathway Involved In Axon Guidance Neuron Projection Extension
Pathways		RHO GTPases Activate Formins RHOD GTPase cycle	Sema3A PAK dependent Axon repulsion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion CRMPs in Sema3A signaling CRMPs in Sema3A signaling Other semaphorin interactions RHOD GTPase cycle RND1 GTPase cycle
Drugs
Diseases
GWAS		Height ( 20881960 25282103) Hip circumference adjusted for BMI ( 34021172) Waist circumference adjusted for body mass index ( 34021172)	Alcoholic chronic pancreatitis ( 28754779) Blood protein levels ( 30072576 29875488) Platelet count ( 32888494) Refractive error ( 32231278) Systolic blood pressure ( 31469255) Weight ( 28552196) Whole-brain volume ( 21116278)
Interacting Genes		13 interacting genes: ACVR1 ADCK5 ADRB2 ANKFY1 BMPR1B DIAPH2 HRAS IHH PLXNA1 SMAD2 SMAD4 SMURF2 TGFBR1	10 interacting genes: AKT1 FES FGFR2 L1CAM NRP1 NRP2 PLXNB1 RHOD RND1 SEMA6D
Entrez ID		29984	5361
HPRD ID		05776	11868
Ensembl ID		ENSG00000173156	ENSG00000114554
Uniprot IDs		E9PIG5 O00212	Q9UIW2
PDB IDs		2J1L
Enriched GO Terms of Interacting Partners?
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