RHOD and DIAPH2

Number of citations of the paper that reports this interaction (PubMedID 12577064)
76

Data Source:
HPRD (in vitro, in vivo)

		RHOD	DIAPH2
Description		ras homolog family member D	diaphanous related formin 2
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Mitochondrial Outer Membrane Early Endosome Cytosol Cytoskeleton Plasma Membrane Cell Cortex Endosome Membrane Cytoplasmic Vesicle Cell Projection	Nucleolus Early Endosome Endoplasmic Reticulum Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	GTPase Activity Guanyl-nucleotide Exchange Factor Activity GTP Binding Protein Kinase Binding	Actin Binding Signaling Receptor Binding Small GTPase Binding
	Biological Process	Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Rho Protein Signal Transduction Regulation Of Cell Shape Cell Migration Lamellipodium Assembly Positive Regulation Of Cell Migration Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Cell Adhesion Focal Adhesion Assembly Regulation Of Catalytic Activity Actin Filament Bundle Assembly Regulation Of Small GTPase Mediated Signal Transduction	Actin Filament Organization Female Gamete Generation Oogenesis
Pathways		RHO GTPases Activate Formins RHOD GTPase cycle	RHOF GTPase cycle
Drugs
Diseases
GWAS		Height ( 20881960 25282103) Hip circumference adjusted for BMI ( 34021172) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		13 interacting genes: ACVR1 ADCK5 ADRB2 ANKFY1 BMPR1B DIAPH2 HRAS IHH PLXNA1 SMAD2 SMAD4 SMURF2 TGFBR1	6 interacting genes: APBB1 CDC42 CENPA NCKIPSD RHOD TCERG1
Entrez ID		29984	1730
HPRD ID		05776	02117
Ensembl ID		ENSG00000173156	ENSG00000147202
Uniprot IDs		E9PIG5 O00212	O60879
PDB IDs		2J1L
Enriched GO Terms of Interacting Partners?
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